Lung Volume Reduction in Emphysema Improves Chest Wall Asynchrony

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Lung Volume Reduction in Emphysema Improves Chest Wall Asynchrony Zaid Zoumot, PhD, Antonella LoMauro, MSc, Andrea Aliverti, PhD, Christopher Nelson, BSc (Hons), Simon Ward, BSc (Hons), Simon Jordan, MD, Michael I. Polkey, PhD, Pallav L. Shah, MD, Nicholas S. Hopkinson, PhD  CHEST  Volume 148, Issue 1, Pages 185-195 (July 2015) DOI: 10.1378/chest.14-2380 Copyright © 2015 The American College of Chest Physicians Terms and Conditions

Figure 1 Optoelectronic plethysmography. A, B, Infrared cameras. C, D, Marker positioning. E-G, Geometric model. 3D = three-dimensional; Vab = abdominal compartment volume; Vcw = total chest wall volume; Vrc,a = abdominal ribcage volume; Vrc,p = pulmonary ribcage volume. (The patients provided written consent for the use of the photographs.) CHEST 2015 148, 185-195DOI: (10.1378/chest.14-2380) Copyright © 2015 The American College of Chest Physicians Terms and Conditions

Figure 2 A, B, Time courses of Vrc,p, Vrc,a, Vab, and Vcw during a typical respiratory cycle during quiet breathing at rest in a representative patient before (A) and after (B) lung volume reduction surgery (LVRS). Black line represents the inspiratory portion of the respiratory cycle, and asynchronous movement of abdominal ribcage compartment (RC,a) before LVRS is clearly demonstrated, as is the improvement thereof after LVRS. Lissajou figures of the dynamic loops of ΔVrc,p vs ΔVrc,a (θRC) and ΔVrc,a vs ΔVab (θDIA) during quiet breathing are used to calculate θ. m = line parallel to the x axis at 50% of one compartment's tidal volume; s = the second compartment's tidal volume. Phase shift is calculated as θ = sin−1 (ms−1). θDIA = phase shift angle between Vrc,p and Vrc,a; θRC = phase shift angle between Vrc,p and Vrc,a. See Figure 1 legend for expansion of other abbreviations. CHEST 2015 148, 185-195DOI: (10.1378/chest.14-2380) Copyright © 2015 The American College of Chest Physicians Terms and Conditions