Figure 4. Histological features of defect healing 7 weeks after defect creation (Masson trichrome staining, scale bar=1 mm). Group 1 (A) showed notable bone regeneration filling most of the defect area. There was also an apparent bone regeneration pattern in the central part of the defect in group 2 (B). Group 3 (C), group 4 (D), and group 5 (E) showed very limited bone regeneration. White asterisks indicate newly formed bone. Black arrowheads indicate defect margin. Figure 4. Histological features of defect healing 7 weeks after defect creation (Masson trichrome staining, scale bar=1 mm). Group 1 (A) showed notable bone regeneration filling most of the defect area. There was also an apparent bone regeneration pattern in the central part of the defect in group 2 (B). Group 3 (C), group 4 (D), and group 5 (E) showed very limited… J Periodontal Implant Sci. 2017 Oct;47(5):339-350. https://doi.org/10.5051/jpis.2017.47.5.339