NVP-BGJ398 inhibits proliferation of a subset of cancer cell lines.

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NVP-BGJ398 inhibits proliferation of a subset of cancer cell lines. NVP-BGJ398 inhibits proliferation of a subset of cancer cell lines. Scatter plot showing IC50 values expressed in μmol/L of NVP-BGJ398 in cell viability assays of cell lines according to cancer type. A total of 5.9% of the cell lines were sensitive to NVP-BGJ398 at concentrations up to 500 nmol/L. Cell lines with the composite “FGFR genetic alterations” feature are indicated in red. Points were jittered horizontally to improve readability. Vito Guagnano et al. Cancer Discovery 2012;2:1118-1133 ©2012 by American Association for Cancer Research