Understanding the Basics of Dementia-Related Psychosis
Dementia
Etiological Subtype of Major and Mild NCDs
Dementia-Related Psychosis
Prevalence of Dementia and DRP in the USA
Diagnosis of DRP
Excluding Non-Dementia-Related Causes for Psychotic Symptoms
Measuring the Type, Frequency, Severity, Pattern, and Timing of Psychosis Symptoms in Clinical Practice
Neurobiology of NPS in Patients With Dementia
Neurobiology of NPS in Patients With Dementia (cont)
Potential Role of Genetics in DRP
Burden of DRP on Caregiver
AA Recommendations for the Nonpharmacologic Approach to BPSD
Rationale for Antipsychotic Therapy
Mechanism of Action of Atypical Antipsychotics
Efficacy of Antipsychotics in Patients With DRP
Safety of Antipsychotics in Patients With DRP
Rationale for SSRI Therapy in DRP
Efficacy and Safety of SSRIs
Rationale for Combining Acetylcholinesterase Inhibitors and Memantine in Treating DRP
Efficacy of AChEI + Memantine on DRP Posthoc Analysis of Pooled Data From 3 RCTs
Efficacy of AChEI + Memantine on DRP Posthoc Analysis of Pooled Data From 3 RCTs
Rational for the Use of Pimavanserin to Treat DRP
Phase 2 RDBPC Trial of the Efficacy and Safety of Pimavanserin in Patients With AD and Psychosis
Phase 2 RDBPC Trial of the Efficacy and Safety of Pimavanserin in Patients With AD Prespecified Subgroup Analysis in Patients With Severe Psychosis
Ongoing Clinical Studies for Psychosis in DPR
Conclusions
Abbreviations
Abbreviations (cont)
Abbreviations (cont)