Depiction of an expiratory flow curve.

Slides:



Advertisements
Similar presentations
Date of download: 5/30/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Mechanical Breath Profile of Airway Pressure Release.
Advertisements

Effects of respiratory rate and tidal volume on evaporative loss at constant intrapulmonary perfluorocarbon volume (10 mL·kg−1) and positive end-expiratory.
Airway pressure and flow waveforms during constant flow volume control ventilation, illustrating the effect of an end-inspiratory breath-hold. Airway pressure.
Lung simulator diagram of airway pressure release ventilation (APRV): volume (yellow), lung pressure (white), and flow (orange)/time curve. Lung simulator.
Immunostaining for lipid peroxidation product 4-hydroxy-2-nonenal (4-HNE) adduct in the lungs of smokers with and without chronic obstructive pulmonary.
Flowchart showing the requirement for starting, documenting and evaluating the effect on quality of life (QoL) of interdisciplinary best supportive care.
Schematic representation of breathing levels during positive expiratory pressure in an obstructed patient. Schematic representation of breathing levels.
Changes of a) spirometric, plethysmographic, and b) impedance data at 5 Hz induced by bronchodilator in flow limited (□) and nonflow limited (▓) patients.
Changes in operating lung volumes expressed as % of predicted total lung capacity (%TLC predicted) are shown as minute ventilation (V′E) increases during.
Kaplan–Meier analysis of survival over 2 years of treatment with riociguat in the CHEST-2 study [54]. Kaplan–Meier analysis of survival over 2 years of.
Extent of interstitial lung disease (ILD) in patients with systemic sclerosis-associated ILD. A simple stratification that utilises pulmonary function.
Representative diaphragm electromyogram (EMG) tracings at rest (a and b) and during maximum voluntary ventilation (c and d) in a healthy subject (a and.
Schematic representations of alveolar units a) in health and b) in chronic obstructive pulmonary disease (COPD), and their corresponding flow versus volume.
Changes in operating lung volumes are shown as ventilation increases with exercise in a) age-matched normal subjects (n = 25) and b) chronic obstructive.
Serial computed tomography (CT) imaging for monitoring disease progression in patients with idiopathic pulmonary fibrosis. Serial computed tomography (CT)
A) Experimental system to carry out a bench test of noninvasive ventilators. a) Experimental system to carry out a bench test of noninvasive ventilators.
A–f) Respiratory mechanical measurements during incremental cycle exercise in patients with moderate chronic obstructive pulmonary disease (COPD) and age-matched.
A) Healthcare utilisation, b) short form (SF)-12 scores and c) work productivity and activity impairment in patients with asthma (▓) and diabetes (▪) in.
Difference of oxygen uptake efficiency (OUE; oxygen uptake (V′O2)/minute ventilation (V′E)) plateau between a typical pulmonary arterial hypertension (PAH)
Change in transpulmonary pressure (PL) from passive to active breathing during a) volume control ventilation (VCV) and b) pressure control ventilation.
A) Breath-holding end-expiration: pleural (Ppl) and transpulmonary (Ptp) pressures in normal subject at the end of expiration. a) Breath-holding end-expiration:
3-year survival of lung cancer patients in the general population and in those with a prior diagnosis of chronic obstructive pulmonary disease (COPD).
Kaplan–Meier survival curves for outcomes among chronic obstructive pulmonary disease (COPD) patients without obstructive sleep apnoea (OSA) (COPD group),
Post-bronchodilator forced expiratory volume in 1 s (FEV1) to forced vital capacity (FVC) ratio in subjects aged >50 yrs. Post-bronchodilator forced expiratory.
Neuromechanical coupling was measured in a subset of patients and expressed as tidal volume (VT) divided by the amplitude of the inspiratory pressure swing.
Nonexpandable lung. a) A single-use digital pleural manometer for use during thoracentesis. b) Pleural elastance curves representing normal, entrapped.
A: Pressure (green) and volume (black)/time curve in airway pressure release ventilation (APRV). A: Pressure (green) and volume (black)/time curve in airway.
Proportion of patients in each World Health Organization functional class (WHO-FC) at the time of pulmonary arterial hypertension-associated systemic sclerosis.
Exertional dyspnoea intensity is shown relative to a) work rate and b) diaphragm electromyography relative to maximum (EMGdi/EMGdi,max) during incremental.
A) Pressure–time and b) flow–time waveforms in the panel of ventilator Astral 150 (ResMed, Bella Vista, Australia). a) The expiratory flow curve does not.
Recordings of quiet tidal breathing at rest, followed by maximal expiration then inspiration. Recordings of quiet tidal breathing at rest, followed by.
Outline of the distal lung regions in haematoxylin and eosin-stained lung tissue [115, 116] showing the inner airway wall (green arrowheads), smooth muscle.
Representative images of computed tomography (CT) scans in patients with small airways disease. a) An inspiratory CT scan in a patient with hypersensitivity.
The minute ventilation (V′E)/carbon dioxide production (V′CO2) relationship slope in a patient with pulmonary arterial hypertension and preserved physiological.
Simulated screenshot of flow starvation in volume control continuous mandatory ventilation. Simulated screenshot of flow starvation in volume control continuous.
Obesity hypoventilation syndrome (OHS) management strategy.
Change in physiological variables from baseline values a) at rest and b) during exercise after saline infusion and exposition to different β-blocker agents.
A) Exertional dyspnoea and b) leg discomfort intensity (Borg score) are shown in response to increasing minute ventilation (V′E) and/or work rate during.
Pathophysiology of obesity hypoventilation syndrome (OHS).
Comparison of airway pressure release ventilation (APRV) (blue curve) and biphasic positive airway pressure (BIPAP) (black curve). Comparison of airway.
In a representative chronic heart failure patient, tidal flow-volume loops at rest (solid line) and at the peak of symptom-limited incremental exercise.
Typical pressure-time curves during forced expiration against an occluded airway in cystic fibrosis (CF) patients and healthy controls. Typical pressure-time.
Relationship between a) forced expiratory flow at 25–75% of forced vital capacity (FVC) (FEF25–75%) and b) forced expiratory flow at 75% of FVC (FEF75%)
Mean pulmonary arterial pressure (Ppa) as a function of cardiac output (Q) at two different levels of pulmonary vascular resistance (PVR). Mean pulmonary.
Cumulative mortality over 60 months in patients with α1-antitrypsin deficiency and an initial forced expiratory volume in 1 s
A) Tidal volume (VT) (presented as % predicted of vital capacity (VC)), b) breathing frequency (Fb), c) dynamic inspiratory capacity (IC) and d) inspiratory.
Effect of respiratory mechanics on cycling of pressure support from inhalation to exhalation. Effect of respiratory mechanics on cycling of pressure support.
Correlation between inspiratory capacity (IC)/total lung capacity (TLC) ratio and oxygen pulse at peak exercise in chronic obstructive pulmonary disease.
Flow, esophageal pressure, airway pressure, and transpulmonary pressure can be used to calculate respiratory system compliance, chest-wall compliance,
A) Tidal volume (VT) plotted as a function of ventilation (V′E), and b) exertional dyspnoea intensity (in Borg scale units) plotted as a function of inspiratory.
Clinical findings in patients with chronic obstructive pulmonary disease according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD)
Examples of ventilatory efficiency slope (minute ventilation (V′E)/carbon dioxide production (V′CO2) slope) in a healthy subject (green line) and a patient.
The gas/tissue ratio, an index of alveolar inflation in normal lung (n=14), supine (□) and prone (○) position, and lung of acute respiratory distress syndrome.
Distribution and change of the underlying disease in patients discharged with home mechanical ventilation (n = 854). ♦: chronic obstructive pulmonary disease;
Technegas® ventilation single photon emission computed tomography images of an asthmatic subject (axial slices) at a) baseline and b) post-methacholine.
A) Operating lung volumes and b) breathing frequency (Fb) during incremental cycle exercise in patients with moderate chronic obstructive pulmonary disease.
Flow, airway pressure, and transversus abdominis electromyogram (EMG) waveforms from a mechanically ventilated patient with COPD receiving pressure-support.
24-h blood pressure profile after a, d) one night of intermittent hypoxia (IH) exposure, b, e) 13 nights IH exposure and c, f) 5 days after cessation of.
Pulmonary artery pressure in a) healthy subjects and b) pulmonary hypertension (PH) subjects. Pulmonary artery pressure in a) healthy subjects and b) pulmonary.
Pathogenesis of acute respiratory distress syndrome (ARDS); the left column represents the alveolar complex coupled with the interstitial space and capillary;
Interventional bronchoscopic and surgical treatments for chronic obstructive pulmonary disease (COPD). Interventional bronchoscopic and surgical treatments.
Airway pressure and flow graphics illustrate delayed cycling.
Mean change from baseline in percentage predicted forced vital capacity (FVC) in the a) phase III CAPACITY [27] and b) ASCEND [14] studies. #: n=174; ¶:
A–f) Diaphragm electromyography (EMGdi) and selected ventilatory and indirect gas exchange responses to incremental cycle exercise test in patients with.
Baseline New York Heart Association functional class (NYHA FC) predicts survival in patients with pulmonary hypertension using infused epoprostenol therapy.
Flow–volume loops of test breaths and preceding control breaths of three representative chronic obstructive pulmonary disease patients with different degrees.
ICU length of stay comparing LTV and HTV mechanical ventilation in adult patients with ARDS. ARDS, acute respiratory distress syndrome; HTV, higher tidal.
Correlation between leg fluid volume (LFV) displacement measured by electrical impedance and apnoea/hypopnoea index (AHI) in non-obese obstructive sleep.
Tracing of tidal breathing followed by an inspiratory manoeuvre to total lung capacity (TLC) to record inspiratory capacity (IC), followed by a full expiration.
Interrelationships are shown between exertional dyspnoea intensity and a) minute ventilation (V′E) and b) the tidal volume (VT)/inspiratory capacity (IC)
Presentation transcript:

Depiction of an expiratory flow curve. Depiction of an expiratory flow curve. A patient with a lung that initially has low compliance has a steeper expiratory flow curve (30°) and will require a short release phase (TLow) (0.3 s in this example) to terminate the expiratory flow rate at 75% of the peak expiratory flow (PEFR). As the lung recruits and becomes more compliant, the slope decreases to 45°, requiring an extension in the TLow time, in this example to 0.5 s. With alveolar recruitment and increasing compliance, the lung is able to accommodate larger tidal volumes. Thus, airway pressure release ventilation allows for mechanical ventilation that is time controlled and adaptive to the patient's respiratory system mechanics (time-controlled adaptive ventilation). Reproduced with permission from the Intensive Care On-line Network (ICON). Michaela Kollisch-Singule et al. Eur Respir Rev 2019;28:180126 ©2019 by European Respiratory Society