Scatter plots of the posterior probability values belonging to normal and IM gastric tissue categories calculated by (A) FP; (B) HW; and (C) integrated FP and HW Raman techniques, respectively, using the PCA-LDA together with leave-one tissue site-out, cros... Scatter plots of the posterior probability values belonging to normal and IM gastric tissue categories calculated by (A) FP; (B) HW; and (C) integrated FP and HW Raman techniques, respectively, using the PCA-LDA together with leave-one tissue site-out, cross-validation methods. The dotted lines (0.5) give the diagnostic sensitivities of 89.3% (25/28), 75.0 % (21/28), and 89.3% (25/28); specificities of 84.4% (249/295), 82.0 % (242/295), and 92.2% (272/295); positive predictive values of 35.2%, 28.4%, and 52.1%; and negative predictive values of 98.8%, 97.2%, and 98.9%, respectively, by using FP, HW, and the integrated FP/HW Raman techniques for separating IM from normal gastric tissue. , normal; , IM. Kan Lin et al. Cancer Prev Res 2016;9:476-483 ©2016 by American Association for Cancer Research