An illustration of experimental transbronchial cryoablation with a rigid cryoprobe (A) and photographs of transbronchial introduction of a cryoprobe (B) and cryoablation (C) on a pig. An illustration of experimental transbronchial cryoablation with a rigid cryoprobe (A) and photographs of transbronchial introduction of a cryoprobe (B) and cryoablation (C) on a pig. A rigid cryoprobe is inserted from the right main bronchus into a distal bronchus through an introducer (B). In the freezing phase, the temperature of the probe tip falls approximately −130°C and the pleura on the frozen lung appears focally whitish with frost (within circle of dashed line) (C). Mitsutomo Kohno et al. BMJ Open Resp Res 2018;5:e000315 ©2018 by British Thoracic Society