Ventricular volumes were measured before and after (24 h) the injection of haemoglobin (25 mg/mL) or saline into wild-type (WT) and in lipocalin 2-deficient.

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Presentation transcript:

Ventricular volumes were measured before and after (24 h) the injection of haemoglobin (25 mg/mL) or saline into wild-type (WT) and in lipocalin 2-deficient (LCN2−/−) mice. Ventricular volumes were measured before and after (24 h) the injection of haemoglobin (25 mg/mL) or saline into wild-type (WT) and in lipocalin 2-deficient (LCN2−/−) mice. Ventricular dilation was calculated as a per cent of presurgery values. Haemoglobin caused marked ventricular dilation in WT mice compared with saline controls, but not LCN2−/− mice. The data represent means±SD, n=5 for each, **p<0.01 versus WT saline group, ##p<0.01 versus LCN2−/− haemoglobin group. Hajime Shishido et al. Stroke Vasc Neurol 2016;1:37-43 Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/