Significant correlation between the initial urine osmolality (Uosm T0) and the variation in plasma sodium (DPNa) after 2 L of isotonic saline in 17 patients with SIADH after water restriction (y = −0.024x + 12.9; r = −0.81; P < 0.001. Significant correlation between the initial urine osmolality (Uosm T0) and the variation in plasma sodium (DPNa) after 2 L of isotonic saline in 17 patients with SIADH after water restriction (y = −0.024x + 12.9; r = −0.81; P < 0.001. Reprinted from reference (36), with permission. Guy Decaux, and Wim Musch CJASN 2008;3:1175-1184 ©2008 by American Society of Nephrology