A: Lesion showing diffuse aggregates of large histiocytoid cells with abundant cytoplasm that admixed with lymphocytes, plasma cells, and neutrophils (hematoxylin.

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A: Lesion showing diffuse aggregates of large histiocytoid cells with abundant cytoplasm that admixed with lymphocytes, plasma cells, and neutrophils (hematoxylin and eosin, magnification × 100). A: Lesion showing diffuse aggregates of large histiocytoid cells with abundant cytoplasm that admixed with lymphocytes, plasma cells, and neutrophils (hematoxylin and eosin, magnification × 100). B: Histiocytoid cells with intact lymphocytes, neutrophils, and erythrocytes within the cytoplasm (hematoxylin and eosin, magnification × 400). C: Immunohistochemistry showed S-100 positively (Envision, magnification × 400). D: Immunohistochemistry showed CD68 positively (Envision, magnification × 400). Hong Ji et al. Respir Care 2012;57:1679-1681 (c) 2012 by Daedalus Enterprises, Inc.