Definitions of primary graft dysfunction after lung transplantation: Differences between bilateral and single lung transplantation Takahiro Oto, MD,

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Presentation transcript:

Definitions of primary graft dysfunction after lung transplantation: Differences between bilateral and single lung transplantation Takahiro Oto, MD, Anne P. Griffiths, FRCNA, Bronwyn J. Levvey, RN, David V. Pilcher, MRCP, Trevor J. Williams, FRACP, Gregory I. Snell, FRACP The Journal of Thoracic and Cardiovascular Surgery Volume 132, Issue 1, Pages 140-147.e2 (July 2006) DOI: 10.1016/j.jtcvs.2006.03.029 Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Pao2/fraction of inspired oxygen (Fio2) ratio in the first 72 hours after transplantation. A, Total lung transplant recipients. B, Subgroup analysis for recipients with chronic obstructive pulmonary disease (COPD). The Journal of Thoracic and Cardiovascular Surgery 2006 132, 140-147.e2DOI: (10.1016/j.jtcvs.2006.03.029) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Prevalence of various Pao2/fraction of inspired oxygen (Fio2) ratios in recipients with chronic obstructive pulmonary disease (COPD) stratified by primary graft dysfunction criteria. A, Bilateral lung transplant recipients. B, Single lung transplant recipients. The Journal of Thoracic and Cardiovascular Surgery 2006 132, 140-147.e2DOI: (10.1016/j.jtcvs.2006.03.029) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Prevalence of various primary graft dysfunction (PGD) grades in recipients with chronic obstructive pulmonary disease (COPD). A, Bilateral lung transplant recipients. B, Single lung transplant recipients. The Journal of Thoracic and Cardiovascular Surgery 2006 132, 140-147.e2DOI: (10.1016/j.jtcvs.2006.03.029) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 Duration of intubation and length of intensive care unit (ICU) stay stratified by primary graft dysfunction (PGD) grades at 0 hours (T0) in recipients with chronic obstructive pulmonary disease (COPD). Patients with a higher grade had longer duration of intubation and ICU stay in both bilateral lung transplantation (BLT) and single lung transplantation (SLT). The Journal of Thoracic and Cardiovascular Surgery 2006 132, 140-147.e2DOI: (10.1016/j.jtcvs.2006.03.029) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure E1 A, Percentage of patients remaining to be intubated. B, Percentage of patients remaining in the intensive care unit (ICU). BLT, Bilateral lung transplantation; COPD, chronic obstructive pulmonary disease; SLT, single lung transplantation. The Journal of Thoracic and Cardiovascular Surgery 2006 132, 140-147.e2DOI: (10.1016/j.jtcvs.2006.03.029) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure E2 Pao2/fraction of inspired oxygen (Fio2) ratio before and after extubation in recipients with chronic obstructive pulmonary disease (COPD). BLT, Bilateral lung transplantation; SLT, single lung transplantation. The Journal of Thoracic and Cardiovascular Surgery 2006 132, 140-147.e2DOI: (10.1016/j.jtcvs.2006.03.029) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions