Figure 3. Proinflammatory activity by Porphyromonas gingivalis-induced oxidized HDL. (A) Monocytes incubated with Porphyromonas gingivalis in the presence.

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Figure 3. Proinflammatory activity by Porphyromonas gingivalis-induced oxidized HDL. (A) Monocytes incubated with Porphyromonas gingivalis in the presence of HDL produced significantly higher levels of TNF-α than monocytes treated with CuSO4 or with HDL alone. (B) Monocytes incubated with Porphyromonas gingivalis and HDL showed higher MMP-9 activity than cells incubated with HDL alone. HDL: high-density lipoprotein, TNF-α: tumor necrosis factor alpha, MMP: matrix metalloproteinase, P.g.: Porphyromonas gingivalis, Control: sample without Porphyromonas gingivalis. a) Statistically significant (P<0.05); b)Statistically significant (P<0.001). Figure 3. Proinflammatory activity by Porphyromonas gingivalis-induced oxidized HDL. (A) Monocytes incubated with Porphyromonas gingivalis in the presence of HDL produced significantly higher levels of TNF-α than monocytes treated with CuSO4 or with HDL alone. (B) Monocytes incubated with Porphyromonas gingivalis and HDL showed… J Periodontal Implant Sci. 2018 Feb;48(1):60-68. https://doi.org/10.5051/jpis.2018.48.1.60