Representative tidal volume (VT) and breathing frequency (f) patterns of subjects with COPD and normal subjects during cardiopulmonary exercise testing. Representative tidal volume (VT) and breathing frequency (f) patterns of subjects with COPD and normal subjects during cardiopulmonary exercise testing. A: COPD subject with inspiratory fraction (IF) 0.15, inspiratory capacity (IC) 1.27, and a 15 W/min work increase. B: COPD subject with IF 0.35, IC 2.49, and a 20 W/min work increase. C: Normal subject with IF 0.44, IC 2.73, and a 20 W/min work increase. Yan Zhang et al. Respir Care 2013;58:1923-1930 (c) 2012 by Daedalus Enterprises, Inc.