Dose-dependent effect of IP6 feeding on angiogenesis in prostate of TRAMP mice. Dose-dependent effect of IP6 feeding on angiogenesis in prostate of TRAMP.

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Dose-dependent effect of IP6 feeding on angiogenesis in prostate of TRAMP mice. Dose-dependent effect of IP6 feeding on angiogenesis in prostate of TRAMP mice. A, representative DCE-MRI images in axial plane of TRAMP prostate/tumor. There are 4 panes per image: a: top left, baseline (before Gd-injection); b: top right, 4 minutes post-gadolinium injection; c: bottom left, 7 minutes post-gadolinium injection; and d: bottom right, 10 minutes post-gadolinium injection. The color scale represents incremental increase in signal intensity in the prostate. B, quantitative assessment of tumor perfusion and permeability for gadolinium uptake in prostate of TRAMP mice fed with IP6. Quantification of parameters is shown as mean and ± SEM (error bars) in each group. NS, not significant. Komal Raina et al. Cancer Prev Res 2013;6:40-50 ©2013 by American Association for Cancer Research