Update on Cystatin C: Incorporation Into Clinical Practice

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Presentation transcript:

Update on Cystatin C: Incorporation Into Clinical Practice Michael G. Shlipak, MD, MPH, Monica D. Mattes, BS, Carmen A. Peralta, MD, MAS American Journal of Kidney Diseases Volume 62, Issue 3, Pages 595-603 (September 2013) DOI: 10.1053/j.ajkd.2013.03.027 Copyright © 2013 National Kidney Foundation, Inc. Terms and Conditions

Figure 1 Cystatin C (Cys C) versus creatinine (Cr) as markers of glomerular filtration rate (GFR). (A) Scatterplot of correlation coefficients (r) for 1/Cys C and 1/Cr with measured GFR. Horizontal line represents the cumulative mean r of all studies analyzed. (B) Scatterplot of receiver operating characteristic plot area under the curve (AUC) values for Cys C and Cr. Horizontal line represents the cumulative mean of all 14 data sets. Adapted and reproduced from Dharnidharka et al7 with permission of the National Kidney Foundation. American Journal of Kidney Diseases 2013 62, 595-603DOI: (10.1053/j.ajkd.2013.03.027) Copyright © 2013 National Kidney Foundation, Inc. Terms and Conditions

Figure 2 Proportion of glomerular filtration rate variance explained by the filtration markers (creatinine and cystatin C) and demographic factors (age and sex, shown in dark grey) in the Berlin Initiative Study. American Journal of Kidney Diseases 2013 62, 595-603DOI: (10.1053/j.ajkd.2013.03.027) Copyright © 2013 National Kidney Foundation, Inc. Terms and Conditions