Ras Brakes for Hippo Developmental Cell

Slides:

Advertisements

Similar presentations

Drosophila SPARC Is a Self-Protective Signal Expressed by Loser Cells during Cell Competition Marta Portela, Sergio Casas-Tinto, Christa Rhiner, Jesús.

Advertisements

A Combined Ex Vivo and In Vivo RNAi Screen for Notch Regulators in Drosophila Reveals an Extensive Notch Interaction Network Abil Saj, Zeynep Arziman,

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.

The RAG Recombinase Dictates Functional Heterogeneity and Cellular Fitness in Natural Killer Cells Jenny M. Karo, David G. Schatz, Joseph C. Sun Cell Volume.

The TEAD/TEF Family of Transcription Factor Scalloped Mediates Hippo Signaling in Organ Size Control Lei Zhang, Fangfang Ren, Qing Zhang, Yongbin Chen,

The Neurobiology of Decision: Consensus and Controversy Joseph W. Kable, Paul W. Glimcher Neuron Volume 63, Issue 6, Pages (September 2009) DOI:

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell

Fatty Acid Trafficking in Starved Cells: Regulation by Lipid Droplet Lipolysis, Autophagy, and Mitochondrial Fusion Dynamics Angelika S. Rambold, Sarah.

Snail1 Is a Transcriptional Effector of FGFR3 Signaling during Chondrogenesis and Achondroplasias Cristina A. de Frutos, Sonia Vega, Miguel Manzanares,

Mitotic Spindle Orientation in Asymmetric and Symmetric Cell Divisions during Animal Development Xavier Morin, Yohanns Bellaïche Developmental Cell Volume.

Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni

Making Proteins in the Powerhouse B. Martin Hällberg, Nils-Göran Larsson Cell Metabolism Volume 20, Issue 2, Pages (August 2014) DOI: /j.cmet

Eph-Ephrin Bidirectional Signaling in Physiology and Disease Elena B. Pasquale Cell Volume 133, Issue 1, Pages (April 2008) DOI: /j.cell

Hemogenic Endothelial Cell Specification Requires c-Kit, Notch Signaling, and p27- Mediated Cell-Cycle Control Kathrina L. Marcelo, Tiffany M. Sills, Suleyman.

Evidence for a Myotomal Hox/Myf Cascade Governing Nonautonomous Control of Rib Specification within Global Vertebral Domains Tânia Vinagre, Natalia Moncaut,

Extracellular Matrix Protein Anosmin Promotes Neural Crest Formation and Regulates FGF, BMP, and WNT Activities Yukinori Endo, Hiroko Ishiwata-Endo, Kenneth.

Transcription Factor Binding to a DNA Zip Code Controls Interchromosomal Clustering at the Nuclear Periphery Donna Garvey Brickner, Sara Ahmed, Lauren.

ER-to-Plasma Membrane Tethering Proteins Regulate Cell Signaling and ER Morphology Andrew G. Manford, Christopher J. Stefan, Helen L. Yuan, Jason A. MacGurn,

Neuronal Cell Types and Connectivity: Lessons from the Retina H. Sebastian Seung, Uygar Sümbül Neuron Volume 83, Issue 6, Pages (September 2014)

Evolution of the Cancer Stem Cell Model Antonija Kreso, John E. Dick Cell Stem Cell Volume 14, Issue 3, Pages (March 2014) DOI: /j.stem

Nuclear Receptors, RXR, and the Big Bang Ronald M. Evans, David J. Mangelsdorf Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell

IPSC Crowdsourcing: A Model for Obtaining Large Panels of Stem Cell Lines for Screening Mahendra Rao Cell Stem Cell Volume 13, Issue 4, Pages (October.

Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.

Keap1/Nrf2 Signaling Regulates Oxidative Stress Tolerance and Lifespan in Drosophila Gerasimos P. Sykiotis, Dirk Bohmann Developmental Cell Volume 14,

The Metabolic Basis of Pulmonary Arterial Hypertension Gopinath Sutendra, Evangelos D. Michelakis Cell Metabolism Volume 19, Issue 4, Pages (April.

Competition between Blown Fuse and WASP for WIP Binding Regulates the Dynamics of WASP-Dependent Actin Polymerization In Vivo Peng Jin, Rui Duan, Fengbao.

Independent Genomic Control of Neuronal Number across Retinal Cell Types Patrick W. Keeley, Irene E. Whitney, Nils R. Madsen, Ace J. St. John, Sarra Borhanian,

CDK Inhibitors: Cell Cycle Regulators and Beyond Arnaud Besson, Steven F. Dowdy, James M. Roberts Developmental Cell Volume 14, Issue 2, Pages

Myc Represses Primitive Endoderm Differentiation in Pluripotent Stem Cells Keriayn N. Smith, Amar M. Singh, Stephen Dalton Cell Stem Cell Volume 7, Issue.

Shaping Genetic Alterations in Human Cancer: The p53 Mutation Paradigm Thierry Soussi, Klas G. Wiman Cancer Cell Volume 12, Issue 4, Pages (October.

LC3 Binding to the Scaffolding Protein JIP1 Regulates Processive Dynein-Driven Transport of Autophagosomes Meng-meng Fu, Jeffrey J. Nirschl, Erika L.F.

Cyclin-Dependent Kinases Control Septin Phosphorylation in Candida albicans Hyphal Development Indrajit Sinha, Yan-Ming Wang, Robin Philp, Chang-Run Li,

Normal and Leukemic Stem Cell Niches: Insights and Therapeutic Opportunities Koen Schepers, Timothy B. Campbell, Emmanuelle Passegué Cell Stem Cell Volume.

Gastrulation Movements: the Logic and the Nuts and Bolts Maria Leptin Developmental Cell Volume 8, Issue 3, Pages (March 2005) DOI: /j.devcel

Quantitative Single-Cell Approaches to Stem Cell Research Martin Etzrodt, Max Endele, Timm Schroeder Cell Stem Cell Volume 15, Issue 5, Pages (November.

Ras Brakes for Hippo Developmental Cell

Tolloid gets Sizzled Competing with Chordin

Volume 13, Issue 1, Pages 5-6 (January 2011)

Targeting TGF-β and the Extracellular Matrix in Marfan's Syndrome

Yorkie and Scalloped: Partners in Growth Activation

Annapoorni Rangarajan, Sue J. Hong, Annie Gifford, Robert A. Weinberg

Where Steroids Meet the Cell Cycle in Architecture

Embryos, Camera, Laser, Action!

Wnt/β-Catenin Signaling: Turning the Switch

Volume 34, Issue 5, Pages (September 2015)

Adaptive Actin Networks

How To Choose a Good Scientific Problem

Small but Mighty: Nanoparticles Probe Cellular Signaling Pathways

Developmental ERK Signaling Goes Digital

William G. Kaelin, Peter J. Ratcliffe Molecular Cell

Eukaryotic Transcription Activation: Right on Target

Ulrike Harjes, Catherine Verfaillie, Peter Carmeliet

At the Intersection of Plant Growth and Immunity

Characterizing the Killer Colorectal Carcinomas

From Cell Structure to Transcription: Hippo Forges a New Path

Volume 130, Issue 6, (September 2007)

Mitotic Chromosomes: Not So Silent After All

Powering Reprogramming with Vitamin C

MicroRNAs in a Cardiac Loop: Progenitor or Myocyte?

Proteins in Plant Brassinosteroid Signaling

Bud Building by Septin Patch Hole Punching

Dynamic Encoding in the Notch Pathway

Lan-Hsin Wang, Nicholas E. Baker Developmental Cell

The Plasticity of Aging: Insights from Long-Lived Mutants

How To Choose a Good Scientific Problem

A BMPy Road for Venous Development

Nerve Control of Blood Vessel Patterning

F.-Nora Vögtle, Chris Meisinger Developmental Cell

Volume 134, Issue 6, (September 2008)

Targeting Protein Stability with a Small Molecule

Presentation transcript:

Ras Brakes for Hippo Developmental Cell Taryn M. Sumabat, Iswar K. Hariharan Developmental Cell Volume 42, Issue 6, Pages 561-562 (September 2017) DOI: 10.1016/j.devcel.2017.09.009 Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 1 The Ras and Hippo Pathways Have Synergistic Effects on Growth (A) Interaction between the Hippo and Ras pathways during normal growth conditions. (B) Combining mutations in the Ras and Hippo pathways causes transcriptional activation of synergistic targets, resulting in massive tissue overgrowth. Developmental Cell 2017 42, 561-562DOI: (10.1016/j.devcel.2017.09.009) Copyright © 2017 Elsevier Inc. Terms and Conditions