A 40-Year-Old Man With Albinism and Progressive Dyspnea

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A 40-Year-Old Man With Albinism and Progressive Dyspnea Gwen Thompson, MD, MPH, Hiroshi Sekiguchi, MD, Dong Chen, MD, PhD, Jay H. Ryu, MD CHEST Volume 154, Issue 5, Pages e143-e146 (November 2018) DOI: 10.1016/j.chest.2018.05.032 Copyright © 2018 American College of Chest Physicians Terms and Conditions

Figure 1 CT scan of the chest at initial presentation demonstrating predominantly peripheral reticular opacities. CHEST 2018 154, e143-e146DOI: (10.1016/j.chest.2018.05.032) Copyright © 2018 American College of Chest Physicians Terms and Conditions

Figure 2 Platelet whole mount electron microscopy image of a platelet from (A) a normal donor and (B) the patient. Arrows indicate the dense granules in a platelet from the normal donor. CHEST 2018 154, e143-e146DOI: (10.1016/j.chest.2018.05.032) Copyright © 2018 American College of Chest Physicians Terms and Conditions

Figure 3 CT scan of the chest at hospital admission demonstrating peripheral reticular opacities with superimposed diffuse ground-glass opacities. CHEST 2018 154, e143-e146DOI: (10.1016/j.chest.2018.05.032) Copyright © 2018 American College of Chest Physicians Terms and Conditions

Figure 4 Extensive alveolar hemosiderosis characterized by accumulation of hemosiderin-laden macrophages in the interstitial septa and alveolar spaces (hematoxylin and eosin staining, 200× original magnification) in a background chronic interstitial fibrosis with usual interstitial pneumonia pattern and superimposed organizing diffuse alveolar damage (not shown). CHEST 2018 154, e143-e146DOI: (10.1016/j.chest.2018.05.032) Copyright © 2018 American College of Chest Physicians Terms and Conditions