A 40-Year-Old Man With Albinism and Progressive Dyspnea

Slides:



Advertisements
Similar presentations
A Man in His 60s With Circulatory Collapse
Advertisements

Polymyositis Associated With Severe Interstitial Lung Disease
A 35-Year-Old Man With Fever, Dyspnea, and Diffuse Reticular Opacities
Rajesh V. Babu, MD, Alicia Romero, MD, Gulshan Sharma, MBBS, MPH, FCCP 
Pulmonary Diffuse Amyloidosis and Ankylosing Spondylitis
Management of Myositis-Related Interstitial Lung Disease
An Elderly Man With Rheumatoid Arthritis and Dyspnea
Volume 77, Issue 4, Pages (April 1980)
Volume 102, Issue 4, Pages (October 1992)
Britta K. Sundquist, MD, Paul G. Comber, MD, PhD, Scott H. Beegle, MD 
Volume 142, Issue 3, Pages (September 2012)
An Unexpected Consequence of Electronic Cigarette Use
A 48-Year-Old Woman With Headache and Respiratory Failure
A Man in His 60s With Circulatory Collapse
Volume 151, Issue 5, Pages e119-e122 (May 2017)
A Young Man With Hemoptysis and Cavitary Lung Lesions
Volume 152, Issue 4, Pages e89-e93 (October 2017)
Volume 145, Issue 3, Pages (March 2014)
Usual Interstitial Pneumonia Complicating Dyskeratosis Congenita
Diffuse Alveolar Hemorrhage Secondary to Apixaban Administration
A 67-Year-Old Man With Psoriatic Arthritis and New-Onset Dyspnea
Volume 140, Issue 1, Pages (July 2011)
A 26-Year-Old Man With a Pleural Effusion and Headache
Peter Hountras, MD, Hector Cajigas, MD  CHEST 
Idiopathic Pulmonary Fibrosis: Evolving Concepts
Acute Exacerbation of Usual Interstitial Pneumonia After Resection of Lung Cancer  Hiroaki Sugiura, MD, Atsuya Takeda, MD, PhD, Toshiko Hoshi, MD, PhD,
Volume 148, Issue 6, Pages e175-e180 (December 2015)
An Elderly Man With Dyspnea and Chest Pain
Britta K. Sundquist, MD, Paul G. Comber, MD, PhD, Scott H. Beegle, MD 
Chok Limsuwat, MD, Philip J. Daroca, MD, Joseph A. Lasky, MD  CHEST 
Volume 148, Issue 3, Pages e80-e85 (September 2015)
Smoking-Related Diffuse Cystic Lung Disease
Recurrent Fevers, Cough, and Pulmonary Opacities in a Middle-Aged Man
Raymond R. Tubbs, D.O., Sanford P. Benjamin, M.D.  CHEST 
Volume 140, Issue 4, Pages (October 2011)
Imaging for the Management of Community-Acquired Pneumonia
Volume 153, Issue 6, Pages e147-e152 (June 2018)
A 56-Year-Old Man With Cardiac Tamponade and Eosinophilia
A 68-Year-Old Man With Dyspnea on Exertion and Cough
A 63-Year-Old Man With Recurrent Dyspnea
Radiation-Induced Pulmonary Veno-occlusive Disease
Volume 132, Issue 6, Pages (December 2007)
Volume 148, Issue 5, Pages e142-e147 (November 2015)
Volume 155, Issue 2, Pages e51-e54 (February 2019)
Diffuse Alveolar Hemorrhage Temporally Related to Cocaine Smoking
Rubinowitz Ami N. , MD, Moon Marianne , MD, Homer Robert , MD, PhD 
Volume 150, Issue 3, Pages e81-e85 (September 2016)
A 57-Year-Old Man With Subacute Progressive Hemoptysis and Fevers
A 7-Year-Old Boy With Sudden Onset of Loud Snoring
An 80-Year-Old Man With Hemoptysis and Unilateral Patchy Opacities
A Man in His 70s Presenting With Chest Pain and Hematuria
A 54-Year-Old Man Referred With Nonresolving Pneumonia
Volume 155, Issue 3, Pages e69-e74 (March 2019)
Sean Connolly, MD, Peter Hountras, MD  CHEST 
Damian R. Compa, MD, Marc A. Judson, MD, FCCP, Scott H. Beegle, MD 
Volume 154, Issue 3, Pages e83-e86 (September 2018)
The Missing Antibody: The Pitfalls of ANCA Testing
Dyspnea on Exertion and Ground-Glass Infiltrates in an Ex-Smoker
Volume 149, Issue 6, Pages (June 2016)
Luke A. Seaburg, MD, Hiroshi Sekiguchi, MD  CHEST 
Volume 155, Issue 4, Pages e91-e96 (April 2019)
Volume 155, Issue 5, Pages e117-e121 (May 2019)
A Man in His 60s With Circulatory Collapse
Ann Vu, MD, Robert Vassallo, MD, Jay H. Ryu, MD  CHEST 
A Woman in Her 80s With Weakness, Hypoxia, and Bone Marrow Granulomas
59-Year-Old Woman With Progressive Dyspnea on Exertion
Volume 156, Issue 2, Pages e41-e45 (August 2019)
A 23-Year-Old Man With Dyspnea During Myasthenia Crisis
A 76-Year-Old Woman With Incidental Right Middle Lobe Atelectasis
A 21-Year-Old Man With “Sloshing” in the Chest
Presentation transcript:

A 40-Year-Old Man With Albinism and Progressive Dyspnea Gwen Thompson, MD, MPH, Hiroshi Sekiguchi, MD, Dong Chen, MD, PhD, Jay H. Ryu, MD  CHEST  Volume 154, Issue 5, Pages e143-e146 (November 2018) DOI: 10.1016/j.chest.2018.05.032 Copyright © 2018 American College of Chest Physicians Terms and Conditions

Figure 1 CT scan of the chest at initial presentation demonstrating predominantly peripheral reticular opacities. CHEST 2018 154, e143-e146DOI: (10.1016/j.chest.2018.05.032) Copyright © 2018 American College of Chest Physicians Terms and Conditions

Figure 2 Platelet whole mount electron microscopy image of a platelet from (A) a normal donor and (B) the patient. Arrows indicate the dense granules in a platelet from the normal donor. CHEST 2018 154, e143-e146DOI: (10.1016/j.chest.2018.05.032) Copyright © 2018 American College of Chest Physicians Terms and Conditions

Figure 3 CT scan of the chest at hospital admission demonstrating peripheral reticular opacities with superimposed diffuse ground-glass opacities. CHEST 2018 154, e143-e146DOI: (10.1016/j.chest.2018.05.032) Copyright © 2018 American College of Chest Physicians Terms and Conditions

Figure 4 Extensive alveolar hemosiderosis characterized by accumulation of hemosiderin-laden macrophages in the interstitial septa and alveolar spaces (hematoxylin and eosin staining, 200× original magnification) in a background chronic interstitial fibrosis with usual interstitial pneumonia pattern and superimposed organizing diffuse alveolar damage (not shown). CHEST 2018 154, e143-e146DOI: (10.1016/j.chest.2018.05.032) Copyright © 2018 American College of Chest Physicians Terms and Conditions