Right ventricular–pulmonary arterial coupling in patients after repair of tetralogy of Fallot  Heiner Latus, MD, Wolfhard Binder, MD, Gunter Kerst, MD,

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Right ventricular–pulmonary arterial coupling in patients after repair of tetralogy of Fallot  Heiner Latus, MD, Wolfhard Binder, MD, Gunter Kerst, MD, Michael Hofbeck, MD, Ludger Sieverding, MD, Christian Apitz, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 146, Issue 6, Pages 1366-1372 (December 2013) DOI: 10.1016/j.jtcvs.2013.02.039 Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Group of pressure-volume loops during preload reduction maneuvers at (A) baseline and (B) dobutamine infusion. The blue line represents the end-systolic pressure volume relation (end-systolic elastance [Ees]) as a parameter of right ventricular contractility; the red line, the slope of the relation connecting the end-systolic and end-diastolic pressure-volume points in the pressure-volume loop that represents the effective pulmonary arterial elastance (Ea). The Journal of Thoracic and Cardiovascular Surgery 2013 146, 1366-1372DOI: (10.1016/j.jtcvs.2013.02.039) Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Relationship between pulmonary arterial elastance (Ea) and indexed pulmonary regurgitant volume (PRVi), right ventricular ejection fraction (RVEF) and brain natriuretic peptide (BNP) levels. The arterial elastance (Ea) showed no correlation with the RV end-diastolic volume relation (EDPVR) as a parameter of the RV intrinsic diastolic function. The Journal of Thoracic and Cardiovascular Surgery 2013 146, 1366-1372DOI: (10.1016/j.jtcvs.2013.02.039) Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Changes in response to dobutamine (mean values) of effective (A) pulmonary arterial elastance (Ea), (B) right ventricular end-systolic elastance (Ees), and (C) right ventricular–pulmonary arterial (RV-PA) coupling Ea/Ees ratio in patients with transannular patch repair (TAP) and in patients who underwent a transatrial/transpulmonary approach. Note the significant difference in RV-PA coupling in response to dobutamine between the 2 groups. The Journal of Thoracic and Cardiovascular Surgery 2013 146, 1366-1372DOI: (10.1016/j.jtcvs.2013.02.039) Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions