Line chart of monthly antibiotic usage rate (AUR) (overall and that in infants with negative blood culture) in relation to the frequency of blood culture-positive sepsis. Line chart of monthly antibiotic usage rate (AUR) (overall and that in infants with negative blood culture) in relation to the frequency of blood culture-positive sepsis. Vasiliki Makri et al. BMJ Open Qual 2018;7:e000285 © Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/