Use Fixed low dose Prothrombin Complex Concentrate (Octaplex)

Slides:

Advertisements

Similar presentations

Rapid Reversal of Warfarin Therapy in Patients with Intracranial / Intraspinal Bleeding Mount Auburn Hospital Blood Bank, Emergency Department, Critical.

Advertisements

EPS R2 Repeat Dispensing compared to typical repeat prescribing systems How it can benefit patients and practices...

What a Bloody Mess! A/Professor Kent Robinson Senior Staff Specialist, Liverpool & Campbelltown Hospitals.

Transfusion Quiz. Q1. What colour blood tube is used for a group and cross match sample? Red Purple Pink Grey.

Transfusion Management of massive haemorrhage in children Ongoing severe bleeding (overt / covert) and received 20ml/kg of red cells or 40ml/kg of any.

Transfusion Quiz Laboratory Staff. Q1. Name 3 patient identifiers that must be on sample taken for Transfusion? Name, ward and gender Surname, Hospital.

Neoteric Technology Ltd – All Rights Reserved - © 2006

A/Prof Larry McNicol. Improves the patient’s own blood and avoids unnecessary transfusions. ‘THE THREE PILLARS’ Minimise blood loss Optimise blood volume.

MAXINE BOYD HOSPITAL TRANSFUSION PRACTITIONER

Transfusion Quiz “Their Lives in Your Hands” Doctors.

MTP Octaplex rFVIIa Calgary. Massive Transfusion Protocol.

New Computer System The Practice is having new computer equipment installed between the dates: 18 th to 20 th February. We would be grateful for your patience.

Octaplex – The Modern PCC

Adam M. Spaulding Emergency Medicine Pharmacist Waterbury Hospital

Kcentra In-service Adam M. Spaulding, PharmD, BCPS

The New Oral Anticoagulants: Handle with Care Philip C. Comp, M.D., Ph.D. October 18, 2013.

Senior clinician Request: a o 4 units RBC o 2 units FFP Consider: a o 1 adult therapeutic dose platelets o tranexamic acid in trauma patients Include:

The direct oral anticoagulants (DOACs) and major trauma Dr Tina Biss Consultant Haematologist Newcastle Hospitals NHS Foundation Trust NTN Annual Trauma.

May 2013 – V0.7 Paediatric Fluid Prescription & Balance Chart HSC Trust’s Policy Collaborative.

Background Methods Results Conclusion Acknowledgements Printed by Multi-Institutional Audit of octaplex® & Comparison with National Recommendations S.

Care of the Anti-coagulated Trauma Patient Julie Mayglothling, MD, FACEP Emergencies in Medicine March 8 th, 2012.

Collection and Administration

Administering Thrombolysis Early Management

FERNE/EMRA How do we treat ICH patients with an elevated INR Andy Jagoda, MD, FACEP Professor and Vice Chair Department of Emergency Medicine Mount Sinai.

Transfusion Management of Massive Haemorrhage in Adults Patient bleeding / collapses Ongoing severe bleeding eg: 150 mls/min and Clinical shock Administer.

Role of Factor Concentrates in Perioperative Coagulopathies Dr Neville Gibbs Department of Anaesthesia Sir Charles Gairdner Hospital.

Improving access to prescriptions with a practice pharmacist Dr Duncan Petty Prescribing Support Services Ltd Research Pharmacist, University of Bradford.

Module 2: Request for blood and blood components

Investigation of Haemostasis MS. c. program Lab-9.

Virginia Clough The Chester Anticoagulant Service Countess of Chester Hospital.

Receive call from designated communication lead in clinical area: ‘This relates to massive haemorrhage situation’ The caller will state: Communication.

Anticoagulants and reversal

Fred V. Plapp MD PhD Pathology and Laboratory Medicine

Idarucizumab (Praxbind®) for Dabigatran Reversal

New policy starts 5th April 2016 IMPORTANT CHANGE TO BLOOD TRANSFUSION SAMPLE REQUIREMENTS Confirmation of a blood group from two samples taken on separate.

Patient Blood Management Guidelines: Module 6 Neonatal and Paediatrics Roles Senior clinician Coordinate team and allocate roles Determine volume and type.

Transfusion Christine Sullivan Transfusion Practitioner.

Pharmacokinetic and Pharmacodynamic Modeling of Andexanet Alfa Dose to Reverse the Anticoagulant Activity of FXa Inhibitors in Patients With Acute Major.

Prothrombin Complex Concentrate- Octaplex

Prothrombin complex concentrate

AUB:Iatrogent Coagulopathy

Fadiea Al-Aieshy PhD-student, MSc Pharm

LTMAD - Beyond CMT Add subtitle

Rapid Reversal of Warfarin Therapy in Patients with Intracranial / Intraspinal Bleeding Mount Auburn Hospital Blood Bank, Emergency Department, Critical.

Warfarin Toxicity Treatment & Management

Evaluation of Four Factor Prothrombin Complex Concentrate

Ortho Warfarin Dosing Protocol

Use of NOACs is contraindicated for AF patients with mechanical prosthetic valves or moderate- severe mitral stenosis (usually of rheumatic origin). Although.

In the name of God. Management trauma in elderly DR. NIKSOLAT GERIATRICIAN ASSISTANT PROFESSOR, IRAN UNIVERSITY OF MEDICAL SCIENCE.

Paediatric Daily Fluid Prescription & Balance Chart 2017

10 Top tips for insulin administration

NAC meeting November 6-7, 2014.

Nubriel Hernandez, PharmD PGY-1 Pharmacy Resident

A Systematic Review On Different Prothrombin Complex Concentrate Strategies To Reverse Vitamin K Antagonist Therapy by Nakisa Khorsand, Hilde A.M. Kooistra,

Truman J. Milling, MD, Scott Kaatz, DO, MSc

Reversal of Direct Oral Anticoagulants (DOAC)

Nova Scotia Update NAC Meeting October 15-16, 2015.

Evidence Supporting Idarucizumab for the Reversal of Dabigatran

DOACs and Urgent Bleeding

Oral Anticoagulant Reversal Agents

Anticoagulant Reversal

Periprocedural Management of Patients on Anticoagulation

 INDICATIONS AND USAGE  DOSAGE AND ADMINISTRATION  DOSAGE FORMS AND STRENGTHS  WARNINGS AND PRECAUTIONS  ADVERSE REACTIONS  USE IN SPECIFIC POPULATIONS.

Bleeding and management of coagulopathy

Journal club govaresh Dr ali gavidel Dr sadr azar.

PCC dose per manufacturer’s instructions.

Arman Qamar et al. JACC 2018;71:

ADAS Anticoagulant Dosing and Advisory Service

RE-ALIGN Randomized, Phase II Study to Evaluate the Safety and Pharmacokinetics of Oral Dabigatran Etexilate in Patients after Heart Valve Replacement.

Drug Summary Info Document Request / monitor Goal of therapy Action

Presentation transcript:

Use Fixed low dose Prothrombin Complex Concentrate (Octaplex) Life, limb or sight threatening haemorrhage or for life-saving emergency surgery in patients on warfarin or DOAC (FXa inhibitors: apixaban, rivaroxaban, edoxaban) Use Fixed low dose Prothrombin Complex Concentrate (Octaplex) Before collecting PCC: For warfarin reversal with INR> 2 (bleeding), or INR> 1.5 (surgery), send coagulation screen and give intravenous 5-10mg Vitamin K For DOAC reversal, send coagulation screen Prescribe 1000iu PCC on fluid prescription chart Send transfusion trained staff to collect PCC from blood product fridge in main theatres or from laboratory At Theatre Batch Product Fridge : Press red emergency button on kiosk, select PCC Remove box labelled as Emergency Octaplex 1000 iu PCC Scan out the product using the barcode on the box label On Ward: Reconstitute using Package Insert instructions Administer using BloodTrack Tx system via the PDA at the bedside After Administration: Reversal of warfarin ensure to take repeat INR after 10 minutes If concern of on-going bleeding to give a further 500iu PCC request via Transfusion Consider discuss with haematologist on-call for guidance if any concern HTT/042 version 2 active 05/07/2019