Volume 5, Issue 8, Pages (August 2019)

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Volume 5, Issue 8, Pages (August 2019)

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Volume 5, Issue 8, Pages 682-685 (August 2019) New-onset autoantibody-mediated nephritis during ustekinumab therapy for psoriasis in patients with and without prior systemic lupus erythematosus Ayida Al Khalili, MD, FRCPC, Leah Scott, MD, FRCPC, Jan P. Dutz, MD, FRCPC JAAD Case Reports Volume 5, Issue 8, Pages 682-685 (August 2019) DOI: 10.1016/j.jdcr.2019.05.022 Copyright © 2019 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Presentation with small plaque/papular psoriasis on sun-exposed areas in a patient with prior SLE (A). Development of proximal nail fold infarcts (B) 10 months after ustekinumab therapy. Periodic acid–Schiff–stained glomerulus shows segmental endocapillary hypercellularity and a small cellular crescent (C). (Original magnification: ×200) JAAD Case Reports 2019 5, 682-685DOI: (10.1016/j.jdcr.2019.05.022) Copyright © 2019 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Palpable purpura in patient with prior psoriasis and psoriatic arthritis at 24 months of ustekinumab therapy (A). Biopsy-confirmed leukocytoclastic vasculitis with perivascular neutrophils, leukocytoclastic debris, and red blood cell extravasation with no vascular immunoglobulin or complement deposition but with full-house granular immune-reactant deposition (IgG, IgM, IgA, C3) at the basement membrane zone (B). (IgG direct immunofluorescence; original magnification, ×100.) JAAD Case Reports 2019 5, 682-685DOI: (10.1016/j.jdcr.2019.05.022) Copyright © 2019 American Academy of Dermatology, Inc. Terms and Conditions