Four classes of agents that can be used to treat multiple myeloma.

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Four classes of agents that can be used to treat multiple myeloma. Four classes of agents that can be used to treat multiple myeloma. Akt, serine-threonine protein kinase B; BRAF, v-Raf murine sarcoma viral oncogene homolog B; HDAC, histone deactylase; MEK, mitogen-activated protein kinase; mTOR, mammalian target of rapamycin; PD, programmed cell death protein; SLAMF7, signaling lymphocytic activation molecule F7. Rimda Wanchoo et al. CJASN 2017;12:176-189 ©2017 by American Society of Nephrology