Superoxide dismutase activity in human follicular fluid after controlled ovarian hyperstimulation in women undergoing in vitro fertilization  Luca Sabatini,

Slides:



Advertisements
Similar presentations
Diminished ovarian reserve as measured by means of baseline follicle-stimulating hormone and antral follicle count is not associated with pregnancy loss.
Advertisements

Changes in serum cortisol and prolactin associated with acupuncture during controlled ovarian hyperstimulation in women undergoing in vitro fertilization–embryo.
Noninvasive metabolomic profiling of embryo culture media using Raman and near- infrared spectroscopy correlates with reproductive potential of embryos.
High concentrations of lactoferrin in the follicular fluid correlate with embryo quality during in vitro fertilization cycles  Atsushi Yanaihara, M.D.,
The human ovarian follicular fluid level of interleukin-8 is associated with follicular size and patient age  Beth A. Malizia, M.D., Yoo Sang Wook, M.D.,
Analysis of follicular fluid and serum markers of oxidative stress in women with infertility related to endometriosis  Laura Prieto, M.D., Juan F. Quesada,
Measurement of inhibin A and inhibin pro-αC in early human pregnancy and their role in the prediction of pregnancy outcome in patients with recurrent.
High soluble CD44 concentration in peritoneal fluid in endometriosis
Joanne F. Dorgan, Ph. D. , Cynthia S. Spittle, Ph. D. , Brian L
Serum levels of inhibins are differentially altered in patients with polycystic ovary syndrome: effects of being overweight and relevance to hyperandrogenism 
Raoul Orvieto, M. D. , M. Sc. , Eduard Hod, M. D
Significance of mRNA levels of connexin37, connexin43, and connexin45 in luteinized granulosa cells of controlled hyperstimulated follicles  Meng-Yin.
Circulating concentration of stem cell factor in serum of stimulated IVF patients  Ali Salmassi, Sandy Zorn, Liselotte Mettler, Kerstin Koch, Walter Jonat,
Seasonal variations and age-related changes in human sperm count, motility, motion parameters, morphology, and white blood cell concentration  Grace M.
Development of a nonsurgical diagnostic tool for endometriosis based on the detection of endometrial leukocyte subsets and serum CA-125 levels  Danièle.
Follicular-phase ovarian follicular fluid and plasma cytokine profiling of natural cycle in vitro fertilization patients  N. Ellissa Baskind, M.B.Ch.B.,
Elevated angiogenin levels in the peritoneal fluid of women with endometriosis correlate with the extent of the disorder  Nobuhiro Suzumori, M.D., Xaio.
Comparative assessment of five serum antimüllerian hormone assays for the diagnosis of polycystic ovary syndrome  Pascal Pigny, Ph.D., Elisse Gorisse,
Day 4 Estradiol Levels Predict Pregnancy Success in Women Undergoing Controlled Ovarian Hyperstimulation for IVF  John Y Phelps, M.D., Adam S Levine,
Changes in synovial fluid and serum concentrations of cartilage oligomeric matrix protein over five years after anterior cruciate ligament rupture  A.
Hakan Cakmak, M. D. , Audra Katz, R. N. , Marcelle I. Cedars, M. D
Reproductive aging and variability in the ovarian antral follicle count: application in the clinical setting  Karl R Hansen, M.D., Ph.D., Jamie L Morris,
Christine L Cook, M. D. , Yong Siow, Ph. D. , Susan Taylor, B. A
Diminished ovarian reserve as measured by means of baseline follicle-stimulating hormone and antral follicle count is not associated with pregnancy loss.
In vitro fertilization versus conversion to intrauterine insemination in Bologna-criteria poor responders: how to decide which option?  Marine Quinquin,
Follicular fluid and serum levels of Inhibin A and pregnancy-associated plasma protein A in patients undergoing IVF  Jiri Moos, Ph.D., Vanda Filova, Ph.D.,
Prospective study of the clinical and laboratory parameters of patients in whom ovarian hyperstimulation syndrome developed during controlled ovarian.
Angela R. Baerwald, Ph. D. , Olufemi A. Olatunbosun, M. D. , Roger A
Effect of 21-day and 24-day oral contraceptive regimens containing gestodene (60 μg) and ethinyl estradiol (15 μg) on ovarian activity  Helen Sullivan,
Robert F. Casper, M.D.  Fertility and Sterility 
In vitro fertilization and pregnancy rates: the influence of sperm motility and morphology on IVF outcome  Eilish T. Donnelly, Ph.D., Sheena E.M. Lewis,
Reliability of automated volumetric measurement of multiple growing follicles in controlled ovarian hyperstimulation  Frederic Lamazou, M.D., Elisangela.
Angela R Baerwald, B. Sc. Hon. , Gregg P Adams, D. V. M. , M. S. , Ph
Clinical Assessment of Recombinant Human Follicle-Stimulating Hormone in Stimulating Ovarian Follicular Development Before In Vitro Fertilization fn1 
Mark D Hornstein, M. D. , Owen K Davis, M. D. , Joe B Massey, M. D
Patients with severe ovarian hyperstimulation syndrome can be managed safely with aggressive outpatient transvaginal paracentesis  Laura P. Smith, M.D.,
Duphaston and human menopausal gonadotropin protocol in normally ovulatory women undergoing controlled ovarian hyperstimulation during in vitro fertilization/intracytoplasmic.
Synchronization of ovarian stimulation with follicle wave emergence in patients undergoing in vitro fertilization with a prior suboptimal response: a.
Peritoneal cytokines and adhesion formation in endometriosis: an inverse association with vascular endothelial growth factor concentration  Ewa Barcz,
Introduction Fertility and Sterility
Pietro Santulli, M. D. , Bruno Borghese, M. D. , Ph. D
Follicle-stimulating hormone or human menopausal gonadotropin for ovarian stimulation in in vitro fertilization cycles: a meta-analysis  Rina Agrawal,
Anti-Müllerian hormone and inhibin B as predictors of pregnancy after treatment by in vitro fertilization/intracytoplasmic sperm injection  Dorothea M.
Testosterone levels in pregnant women correlate with the insulin response during the glucose tolerance test  Anuja Dokras, M.D., Ph.D., Robert Z Spaczynski,
Diminished intrafollicular estradiol levels in in vitro fertilization cycles from women with reduced ovarian response to recombinant human follicle-stimulating.
Correlations between concentrations of interleukin-12 and interleukin-13 and lymphocyte subsets in the follicular fluid of women with and without polycystic.
Concentrations of inhibins and activin in women undergoing stimulation with recombinant follicle-stimulating hormone for in vitro fertilization treatment 
Orhan Bukulmez, M. D. , Bruce R. Carr, M. D. , Kathleen M. Doody, M. D
In vitro fertilization versus conversion to intrauterine insemination in the setting of three or fewer follicles: how should patients proceed when follicular.
Intrauterine insemination results are not affected if Hysterosalpingo Contrast Sonography is used as the sole test of tubal patency  Judith Hamilton,
Endocrine gland–derived vascular endothelial growth factor concentrations in follicular fluid and serum may predict ovarian hyperstimulation syndrome.
Concentration of vascular endothelial growth factor released by cultured human luteinized granulosa cells is higher in women with polycystic ovaries than.
Inducible nitric oxide synthase expression by peritoneal macrophages in endometriosis- associated infertility  Barbara H Osborn, M.D., A.F Haney, M.D.,
Markedly elevated plasma myeloperoxidase protein in patients with pelvic inflammatory disease who have A allele myeloperoxidase gene polymorphism  Shun-An.
Pyridostigmine cotreatment for controlled ovarian hyperstimulation in low responders undergoing in vitro fertilization–embryo transfer  Chung-Hoon Kim,
Decreased levels of interleukin-18 in peritoneal fluid but not in serum of patients with endometriosis  Xinmei Zhang, M.D., Jun Lin, M.D., Yuli Qian,
Human granulosa-lutein cell in vitro production of progesterone, inhibin A, inhibin B, and activin A are dependent on follicular size and not the presence.
CD11c+HLADR+ dendritic cells are present in human ovarian follicular fluid, and their maturity correlates with serum estradiol levels in response to gonadotropins 
Withholding gonadotropins (“coasting”) to minimize the risk of ovarian hyperstimulation during superovulation and in vitro fertilization–embryo transfer.
Women with regular menstrual cycles and a poor response to ovarian hyperstimulation for in vitro fertilization exhibit follicular phase characteristics.
Percutaneous oocyte retrieval from an inguinal ovary
Ariel Fuentes, M. D. , Alex Muñoz, B. S. , Kurt Barnhart, M. D
Soluble ICAM-1 and E-selectin levels correlate with clinical and biological aspects of severe ovarian hyperstimulation syndome  Yoram Abramov, M.D., Joseph.
Divergent effects of the 677C>T mutation of the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene on ovarian responsiveness and anti-Müllerian hormone.
Transforming growth factor-β1 and its receptor soluble endoglin are altered in polycystic ovary syndrome during controlled ovarian stimulation  Reshef.
Early follicular serum müllerian-inhibiting substance levels are associated with ovarian response during assisted reproductive technology cycles  David.
Altered circulating levels of matrix metalloproteinases 2 and 9 and their inhibitors and effect of progesterone supplementation in women with endometriosis.
Transient hyperandrogenemia and its relation to ovulation
Effect of methotrexate exposure on subsequent fertility in women undergoing controlled ovarian stimulation  Janet F. McLaren, M.D., Richard O. Burney,
Matrix metalloproteinase (MMP-1) and tissue inhibitor of MMP in peritoneal fluids and sera and correlation with peritoneal adhesions  Nasser Chegini,
Presentation transcript:

Superoxide dismutase activity in human follicular fluid after controlled ovarian hyperstimulation in women undergoing in vitro fertilization  Luca Sabatini, M.D., Claire Wilson, B.Sc., Adrian Lower, Talha Al-Shawaf, M.D., J.Gedis Grudzinskas, M.D.  Fertility and Sterility  Volume 72, Issue 6, Pages 1027-1034 (December 1999) DOI: 10.1016/S0015-0282(99)00411-2

FIGURE 1 Total protein concentration (A) and superoxide dismutase activity (B) samples of FF (n = 114) and serum (n = 28). The boxes represent the 25th–75th percentile points of the data; also shown are the 50th percentile (horizontal line) and the mean (dashed line). Bars represent the 10th and 90th percentiles and circles represent the 5th and 95th percentiles. ∗P<.001, determined by Student’s t test. †P<.001, determined by Mann-Whitney U test. Sabatini. Superoxide dismutase activity. Fertil Steril 1999. Fertility and Sterility 1999 72, 1027-1034DOI: (10.1016/S0015-0282(99)00411-2)

FIGURE 2 Correlation between superoxide dismutase activity in FF and serum. Each point represents a single follicle’s superoxide dismutase activity and the corresponding serum activity from an individual patient. The 95% confidence intervals are shown above and beneath the regression line (r = 0.552; P<.0001; 95% confidence interval, 0.40–0.67 by Spearman’s rank correlation analysis). Sabatini. Superoxide dismutase activity. Fertil Steril 1999. Fertility and Sterility 1999 72, 1027-1034DOI: (10.1016/S0015-0282(99)00411-2)

FIGURE 3 Correlation between protein concentrations in FF and serum. Each point represents a single follicle’s total protein concentration and the corresponding serum concentration from an individual patient. The 95% confidence intervals are shown above and beneath the regression line (r = 0.346; P<.0002; 95% confidence interval, 0.17–0.50 by Pearson’s correlation analysis). Sabatini. Superoxide dismutase activity. Fertil Steril 1999. Fertility and Sterility 1999 72, 1027-1034DOI: (10.1016/S0015-0282(99)00411-2)