TUF Love for “Junk” DNA Cell

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TUF Love for “Junk” DNA Cell Aarron T. Willingham, Thomas R. Gingeras Cell Volume 125, Issue 7, Pages 1215-1220 (June 2006) DOI: 10.1016/j.cell.2006.06.009 Copyright © 2006 Elsevier Inc. Terms and Conditions

Figure 1 Discovery Timeline of Noncoding RNAs This timeline highlights the discoveries of the different functional classes of noncoding RNAs (ncRNAs) and the emergence of evidence for widespread transcription throughout the genome. Widespread transcription produces of a plethora of unannotated RNA species, most of which are characterized by reduced protein coding potential. Examples of the many regulatory roles of ncRNAs in cellular processes are provided. Diversity in the size and function of ncRNAs coupled with the abundance of noncoding transcription suggest that many ncRNAs still await discovery. (See Table S1 for full citations for timeline events). Cell 2006 125, 1215-1220DOI: (10.1016/j.cell.2006.06.009) Copyright © 2006 Elsevier Inc. Terms and Conditions