A schematic of the fetal circulation before birth and the changes in flow that occur after birth. A schematic of the fetal circulation before birth and.

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Presentation transcript:

A schematic of the fetal circulation before birth and the changes in flow that occur after birth. A schematic of the fetal circulation before birth and the changes in flow that occur after birth. Before birth the major supply of preload for the left ventricle is derived from the placental circulation, which passes from the umbilical vein through the ductus venosus, inferior vena cava and foramen ovale to directly enter the left side of the heart; thereby bypassing the right side of the heart and the lungs (A; pathway shown by red arrow). As most blood exiting the right ventricle passes through the ductus arteriosus (A; red arrow) and enters the descending aorta, very little blood flows into the fetal lungs before birth. After birth, the supply of blood for the left ventricle derived from the placental circulation is lost (B; broken red arrow) and so preload for the left ventricle becomes dependent on pulmonary venous return (B; red arrow). For this to occur, the lung must first aerate, which triggers a decrease in pulmonary vascular resistance, allowing all of right ventricular output to pass through the lungs (B; red arrow). In addition, flow through the ductus arteriosus reverses so that left ventricular output becomes a major contributor to pulmonary blood flow and, therefore to pulmonary venous return as well. Stuart B Hooper et al. Arch Dis Child Fetal Neonatal Ed 2015;100:F355-F360 Copyright © BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health. All rights reserved.