The higher dose of rhNGF at 20 µg/mL concentration showed improvement of lacrimal function at each time point (*p<0.05). rhNGF, recombinant human nerve growth factor; TBUT, tear film break-up time. The higher dose of rhNGF at 20 µg/mL concentration showed improvement of lacrimal function at each time point (*p<0.05). rhNGF, recombinant human nerve growth factor; TBUT, tear film break-up time. Marta Sacchetti et al. Br J Ophthalmol doi:10.1136/bjophthalmol-2018-312470 ©2019 by BMJ Publishing Group Ltd.