Meningeal γδ T cell homeostasis is independent of inflammatory signals

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Presentation transcript:

Meningeal γδ T cell homeostasis is independent of inflammatory signals. Meningeal γδ T cell homeostasis is independent of inflammatory signals. Cell suspensions were prepared from the meninges of 8- to 12-week-old C57BL/6J WT mice, bred in an SPF (A to D) versus GF (A) environment, treated or not with an antibiotic cocktail (Abx) (B), and compared with IL-1R−/−, IL-23R−/− (C), TLR2−/−, TLR4−/−, Caspase 1−/−, and NOD1−/− mice (D). Percentages of γδ T cells and IL-17 producers were analyzed by FACS as illustrated in Fig. 1. Results are representative of two to four independent experiments. Miguel Ribeiro et al. Sci. Immunol. 2019;4:eaay5199 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works