Proteome changes associated with CHCHD2 expression in NSCLC cells.

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Proteome changes associated with CHCHD2 expression in NSCLC cells. Proteome changes associated with CHCHD2 expression in NSCLC cells. A, Venn diagram depicting the number of nonredundant proteins identified in CHCHD2 knockdown, rescue/overexpression (RES/OE), and control (NSC) groups. Label-free quantitative proteome analysis was performed on six NSCLC cell lines (NSC, knockdown, and RES/OE derivatives of HCC827 and LPC43). B, enriched GO biologic process terms from proteins differentially expressed between CHCHD2 knockdown and control cells. Yuhong Wei et al. Mol Cancer Res 2015;13:1119-1129 ©2015 by American Association for Cancer Research