Enhancing flow synchrony with a variable flow, pressure-targeted breath. Enhancing flow synchrony with a variable flow, pressure-targeted breath. In the left column, a flow-targeted breath is delivered but the flow is inadequate for patient demand and asynchrony is manifest by the deeply coved airway-pressure profile (solid arrow). In contrast, the pressure-targeted breath (right column) is set to deliver a similar VT, but the variable flow of the pressure-targeted breath (dashed arrow) synchronizes better with patient effort, providing a smoother, more constantly positive airway pressure profile. (Adapted from Reference 29, with permission.) Neil R MacIntyre Respir Care 2011;56:73-84 (c) 2012 by Daedalus Enterprises, Inc.