Matrix metalloproteinase (MMP-1) and tissue inhibitor of MMP in peritoneal fluids and sera and correlation with peritoneal adhesions Nasser Chegini,

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Matrix metalloproteinase (MMP-1) and tissue inhibitor of MMP in peritoneal fluids and sera and correlation with peritoneal adhesions Nasser Chegini, Ph.D., Kristina Kotseos, B.Sc., Barbara Bennett, M.D., Michael P. Diamond, M.D., Lena Holmdahl, M.D., Ph.D., James Burns, Ph.D. Fertility and Sterility Volume 76, Issue 6, Pages 1207-1211 (December 2001) DOI: 10.1016/S0015-0282(01)02874-6

FIGURE 1 Notched box plots showing the distribution of MMP-1 (A), TIMP-1 (B), and MMP1/TIMP1 complex (C) in serum and peritoneal fluid. The vertical line within the box boundaries represents the distribution of the middle 50%, the thin horizontal lines within the boxes are the median, and the thick lines are the arithmetic mean. The notches show the 95th percentile and the error bars, the 90th and 10th percentiles. In A, B, and C, serum level (∗) differs from peritoneal fluid level (P. Fluid; P=.01, .02, and .03, respectively). Chegini. MMP/TIMP and adhesions. Fertil Steril 2001. Fertility and Sterility 2001 76, 1207-1211DOI: (10.1016/S0015-0282(01)02874-6)

FIGURE 2 The levels (mean ± SEM) of MMP-1 (A), TIMP-1 (B), and MMP-1/TIMP1 complex (C) in serum and PF of subjects with extensive, moderate, and mild adhesions, and without adhesions. There was no significant difference in MMP-1, TIMP-1, or MMP-1-TIMP-1 complex levels among the groups, with the exception of TIMP-1 in PF of subjects with extensive adhesions. ∗, ∗∗Statistically significant difference between these groups (P<.05). No-Adhs = no adhesion. Chegini. MMP/TIMP and adhesions. Fertil Steril 2001. Fertility and Sterility 2001 76, 1207-1211DOI: (10.1016/S0015-0282(01)02874-6)