Relationship between the ΔP0. 1/end-tidal CO2 (ΔP0 Relationship between the ΔP0.1/end-tidal CO2 (ΔP0.1/ΔPETCO2) slope and the ΔPETCO2 in subjects with late-onset Pompe disease and healthy controls. Relationship between the ΔP0.1/end-tidal CO2 (ΔP0.1/ΔPETCO2) slope and the ΔPETCO2 in subjects with late-onset Pompe disease and healthy controls. Note that 11 late-onset Pompe disease subjects (84.6%) showed a reduced hypercapnic drive response (slope below the 25% interquartile level), whereas 9 (69.2%) had a slope below the 5% interquartile level. Eduardo L De Vito et al. Respir Care 2016;61:930-935 (c) 2012 by Daedalus Enterprises, Inc.