Comparison of pre- and post-bronchodilator data for spirometric and oscillometric parameters. Comparison of pre- and post-bronchodilator data for spirometric.

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Comparison of pre- and post-bronchodilator data for spirometric and oscillometric parameters. Comparison of pre- and post-bronchodilator data for spirometric and oscillometric parameters. Dotted lines denote the limits of normal. Paired comparisons revealed that the normal control and smoker normal forced oscillation technique (FOT) groups did not demonstrate bronchodilator response of either forced expiratory volume in 1 s (FEV1) or any of the FOT parameters. a) A statistically significant increase in FEV1 was noted in the smoker abnormal FOT group, but an increase >12% was evident in only a single individual. In addition, the smoker abnormal FOT group demonstrated significant bronchodilator response for b) resistance at 5 Hz (R5; p=0.011), c) dynamic elastance as assessed by reactance at 5 Hz (X5; p=0.008) and d) frequency dependence of resistance (R5–20; p=0.022). Kenneth I. Berger et al. ERJ Open Res 2016;2:00066-2016 ©2016 by European Respiratory Society