Management of NTM Lung Disease

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Presentation transcript:

Management of NTM Lung Disease

Overview of NTM Lung Disease

Overview of NTM Lung Disease (cont)

Incidence and Prevalence of NTM Lung Disease Oregon

Importance of Early Identification Diagnosis

ATS/IDSA Diagnostic Criteria

Susceptibility Testing, Slow-Growing M. Kansasii

Susceptibility Testing Slow-Growing: MAC

Susceptibility Testing Fast-Growing: M. Abscessus

NTM Lung Disease Complementary Approaches

Which Patients Require Antibiotic Therapy?

Cavitary vs Noncavitary NTM Lung Disease

Treatment of Macrolide-Susceptible NTM Lung Disease

Treatment for M Abscessus

Treatment for M Kansasii

Limitations of Standard Care

Treatment-Related AEs

ALIS Overview

Phase 3 CONVERT Trial

CONVERT Findings

Adverse Events

ALIS as a New Agent in the NTM Treatment Armamentarium

Clofazimine Overview

Clofazimine Observational Cohort Study

Clofazimine Safety

Bedaquiline Overview

Bedaquiline Findings

Oxazolidinones Tedizolid, Linezolid

Concluding Remarks

Abbreviations

Abbreviations (cont)