The Role of TET2 in Hematologic Neoplasms

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Presentation transcript:

The Role of TET2 in Hematologic Neoplasms Linda Holmfeldt, Charles G. Mullighan Cancer Cell Volume 20, Issue 1, Pages 1-2 (July 2011) DOI: 10.1016/j.ccr.2011.06.025 Copyright © 2011 Elsevier Inc. Terms and Conditions

Figure 1 Schematic of the Regulatory Network of TET2 HSC, hematopoietic stem cell; mC, 5-methyl-cytosine. 2-Hydroxyglutarate is the metabolic product of mutated, neomorphic IDH1 and IDH2 proteins. Cancer Cell 2011 20, 1-2DOI: (10.1016/j.ccr.2011.06.025) Copyright © 2011 Elsevier Inc. Terms and Conditions