Clinical success of intrauterine insemination cycles is affected by the sperm preparation time  Patricia Fauque, M.D., Ph.D., Philippe Lehert, Ph.D., Marjorie Lamotte, M.D., Karima Bettahar-Lebugle, M.D., Alphée Bailly, M.D., Catherine Diligent, M.D., Michel Clédat, M.D., Paul Pierrot, M.D., Marie-Lorraine Guénédal, M.D., Paul Sagot, M.D.  Fertility and Sterility  Volume 101, Issue 6, Pages 1618-1623.e3 (June 2014) DOI: 10.1016/j.fertnstert.2014.03.015 Copyright © 2014 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Dependence between the time interval from the end of sperm preparation to intrauterine insemination and observed clinical pregnancy (CP) rate. Points are observed CP rates associated with groups of cycles with intervals from 0 to 180 minutes by steps of 20 minutes and estimated with the use of polynomial quadratic regression. Fertility and Sterility 2014 101, 1618-1623.e3DOI: (10.1016/j.fertnstert.2014.03.015) Copyright © 2014 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Probability of response (clinical pregnancy) depending on the time interval from the end of sperm preparation to intrauterine insemination (TSP) for four conditions of patients, from top to bottom: curve 1: women 25 years old, within total motile sperm count (TMSC) optimal range, and no unexplained infertility: these patients were associated with the highest response rate, with a maximum value when TSP is in the range of 40–80 minutes; curve 2: similar to (1) but for women 35 years old (instead of 25); curve 3: similar to (2) but for women outside the optimal TMSC of 1–11 × 106 (with male factor [MF]); and curve 4: similar to (3), but for women with unexplained infertility (UI): these patients were associated with the worst prognosis. Fertility and Sterility 2014 101, 1618-1623.e3DOI: (10.1016/j.fertnstert.2014.03.015) Copyright © 2014 American Society for Reproductive Medicine Terms and Conditions