Most virus-related pyrosequencing reads found in raw sewage represent previously unknown viruses. Most virus-related pyrosequencing reads found in raw.

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Most virus-related pyrosequencing reads found in raw sewage represent previously unknown viruses. Most virus-related pyrosequencing reads found in raw sewage represent previously unknown viruses. Diversity plot of selected viral families (only the prefix of a family name is shown) are organized by genomic content (dsDNA, ssDNA, ssRNA, and dsRNA). The four phage families are underlined. The rings of the plot represent bins of increasing percent identity (20%, 50%, and 100% are marked for orientation) relative to the GenBank reference sequence as identified by the top BLAST hit. The area of each circle is proportional to the number of virus family reads in that location. The geographic locations from which the sequence reads were obtained are indicated by color: blue, Addis Ababa, Ethiopia; green, Barcelona, Spain; red, Pittsburgh, PA, USA. Paul G. Cantalupo et al. mBio 2011; doi:10.1128/mBio.00180-11