Cavoaortic shunt improves hemodynamics with preserved oxygen delivery in experimental right ventricular failure during left ventricular assist device.

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Presentation transcript:

Cavoaortic shunt improves hemodynamics with preserved oxygen delivery in experimental right ventricular failure during left ventricular assist device therapy Per Vikholm, MD, Petter Schiller, MD, Jakob Johansson, MD, PhD, Laila Hellgren, MD, PhD The Journal of Thoracic and Cardiovascular Surgery Volume 147, Issue 2, Pages 625-631 (February 2014) DOI: 10.1016/j.jtcvs.2013.02.010 Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Animal preparation and flow chart of the experimental protocol in the model of right ventricular failure in pigs (n = 10). An LVAD was implanted and a cavoaortic shunt was created from the right atrium (the cannulas into the superior vena cava) to the aorta. LVAD, Left ventricular assist device. The Journal of Thoracic and Cardiovascular Surgery 2014 147, 625-631DOI: (10.1016/j.jtcvs.2013.02.010) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Right atrial and right ventricular pressures at baseline, RV failure, LVAD, and LVAD + cavoaortic shunt (n = 10). RAP, Right atrial pressure; DRVP, diastolic right ventricular pressure; SRVP, systolic right ventricular pressure; LVAD, left ventricular assist device. The Journal of Thoracic and Cardiovascular Surgery 2014 147, 625-631DOI: (10.1016/j.jtcvs.2013.02.010) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Systemic oxygen saturation (arterial and venous) at baseline, right ventricular failure, LVAD, and LVAD + cavoaortic shunt (n = 10). Sao2, Arterial oxygen saturation; Svo2, venous oxygen saturation; LVAD, left ventricular assist device. The Journal of Thoracic and Cardiovascular Surgery 2014 147, 625-631DOI: (10.1016/j.jtcvs.2013.02.010) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 Oxygen delivery (Do2) and oxygen consumption (Vo2) at baseline, right ventricular failure, LVAD, and LVAD + cavoaortic shunt (n = 10). LVAD, Left ventricular assist device. The Journal of Thoracic and Cardiovascular Surgery 2014 147, 625-631DOI: (10.1016/j.jtcvs.2013.02.010) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions