Fig. 2 Short-term synaptic plasticity.

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Biological Modeling of Neural Networks Week 6 Hebbian LEARNING and ASSOCIATIVE MEMORY Wulfram Gerstner EPFL, Lausanne, Switzerland 6.1 Synaptic Plasticity.

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Fig. 2 Short-term synaptic plasticity. Short-term synaptic plasticity. (A) Schematic of application of presynaptic spikes to a postneuron through a synaptic joint. (B) Schematic of application of electrical pulses to an ONW ST analogous to presynaptic spikes that induces current responses through the ONW active channel. (C) EPSC triggered by a negative presynaptic spike (−1 V, 50 ms). (D) IPSC triggered by a positive presynaptic spike (1 V, 50 ms). (E) EPSCs triggered by two spikes, with an interspike interval of 780 ms. A1 and A2, amplitudes of the first and second EPSCs, respectively. (F) Schematic of applying spatiotemporally correlated presynaptic spikes onto a postneuron through two presynaptic connections to one single strand of dendrite. (G) Schematic of EPSC triggered by a pair of spatiotemporally correlated spikes applied to an ONW ST through two laterally coupled gates. (H) EPSC triggered by a single or pair of spatiotemporally correlated presynaptic spikes versus time. (I) Amplitude of the EPSC at t = 0 (when the spike is applied to synapse 1) versus interval Δtpre2 − pre1 between the spikes. Wentao Xu et al. Sci Adv 2016;2:e1501326 Copyright © 2016, The Authors