Fig. 2 Demonstration of directional self-organization via Mimosa Origami self-assembly. Demonstration of directional self-organization via Mimosa Origami self-assembly. (A) Optical photographs of the spontaneous directional self-organization response of a rectangular-shaped Janus bilayer. A pinpoint water droplet stimulus results in the immediate self-assembly of a centimeter-long microchannel. (B) This rapid motion is reminiscent of the stimulus-response propagation during the negative tropism of the M. pudica’s leaflets. (C) The folded Janus bilayers are spontaneously unfolded by immersion in an ethanol bath. Restoration of the initial surface properties allows a novel folding cycle, demonstrating the full reversibility of this self-organization state. (D) FTIR spectroscopic analysis showing the variation in the surface composition of the Janus bilayer during the folding and unfolding cycle. (E) Schematic illustrations of capillary-induced unfolding of the self-assembled microchannel. William S. Y. Wong et al. Sci Adv 2016;2:e1600417 Copyright © 2016, The Authors