Thromboelastometry-guided administration of fibrinogen concentrate for the treatment of excessive intraoperative bleeding in thoracoabdominal aortic aneurysm.

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Thromboelastometry-guided administration of fibrinogen concentrate for the treatment of excessive intraoperative bleeding in thoracoabdominal aortic aneurysm surgery  Niels Rahe-Meyer, MD, MSc, PhD, Cristina Solomon, MD, Michael Winterhalter, MD, Siegfried Piepenbrock, MD, Kenichi Tanaka, MD, MSc, PhD, Axel Haverich, MD, Maximilian Pichlmaier, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 138, Issue 3, Pages 694-702 (September 2009) DOI: 10.1016/j.jtcvs.2008.11.065 Copyright © 2009 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Flow chart of transfusion algorithm. Platelet count is expressed as 1000/μL. PLT, Platelet count measured at the last suture time point (the suture of the last collateral artery on the aortic graft); FFP, fresh frozen plasma; PC, platelet concentrates. The Journal of Thoracic and Cardiovascular Surgery 2009 138, 694-702DOI: (10.1016/j.jtcvs.2008.11.065) Copyright © 2009 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Examples of thromboelastometry curves (ROTEM). A, Traces before fibrinogen concentrate therapy. The upper MCF limit of 68 mm is indicated by a solid line. B, Traces after fibrinogen concentrate therapy. MCF, Maximum clot firmness; EXTEM, ROTEM test with extrinsic activation of coagulation; FIBTEM, ROTEM test with extrinsic activation of coagulation and platelet inhibition with cytochalasin D. The Journal of Thoracic and Cardiovascular Surgery 2009 138, 694-702DOI: (10.1016/j.jtcvs.2008.11.065) Copyright © 2009 The American Association for Thoracic Surgery Terms and Conditions