Introduction to pathology

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Introduction to Pathology By Dr. Gehan Mohamed Dr. Abdelaty Shawky.

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Introduction to pathology 2019

course 2 credit hour Three instuctors: Dr Heyam Awad, Dr Mousa Abbadi and Dr Manar Hajeer

Reference Robbins basic pathology Tenth edition Web Path Internet teaching http://library.med.utah.edu/WebPath/EXAM/MULTGEN/examidx.htm

Course description lecture topic lecturer 5 Cell injury Dr manar 6 inflammation Dr mousa 3 repair 11 neoplasia Dr heyam

evaluation Midterm exam… .. 40 marks Final exam……50 marks Attendance… 10 marks

Contact details Dr Manar hajeer E-mail: M.hajeer83@hotmail.com Office: third floor , clinics building, JUH

What is pathology The study (logos) of suffering or disease (pathos). The study of the structural, biochemical, and functional changes in cells, tissues, and organs that are involved by disease.

Why pathology is important A bridge between the basic sciences and clinical medicine. Uses molecular, microbiologic, immunologic, and morphologic techniques trying to reach a diagnosis and explanation.

Divisions General pathology: Cell injury, inflammation and repair, hemodynamic disorders, genetic disorders, immune system diseases, infectious disease and environmental diseases. Systemic pathology: alterations in specialized organs and tissues in diseased status.

Aspects of disease Epidemiological aspects Etiology/ cause: Genetic: mutations Acquired: infectious, nutritional, chemical..

Aspects of disease Pathogenesis: sequence of events in the response of cells or tissues to the etiologic agent, from the initial stimulus to the ultimate expression of the disease. (mechanism).

Aspects of disease Molecular changes. Morphologic changes: macroscopic versus microscopic. Clinical features including biochemical tests, physical findings, radiological findings Complications Treatment Prognosis

Classification of Pathology Anatomical/ surgical pathology or histopathology: Gross examination and microscopic examination to reach a diagnosis. Clinical pathology: hematology, microbiology, immunology and biochemistry.

Anatomic pathology Histopathology. Cytopathology. Autopsy. Subspecialties: neuropathology, dermatopathology, oral pathology……

Diagnosis in Histopathology Biopsies: excisional and incisional. Smears: exfoliative and fine needle aspiration.