PfHsp70x knockout does not inhibit export of PfEMP1 to the host cell.

Slides:

Advertisements

Similar presentations

Figure S1 a b c d DAPI Lgr β-catenin Merge

Advertisements

Supplementary Figure 2 Secondary transplanted brain tumors from PASC1 express human GH. Immuno-fluorescence staining of brain sections from mice implanted.

CD4+ICOS+IL-4+ TFH cells are sparse in human SLOs.

Peixoto et al, Supplementary Figure 4.1 A(top)

Malaria Parasite Invasion: Achieving Superb Resolution

UUKV NSs interacts with MAVS

Malaria Parasite Invasion: Achieving Superb Resolution

Alveolar lymphangiogenesis is a feature of idiopathic pulmonary fibrosis (IPF). a) Tissue sections reacted with anti-D2-40 (brown) and anti-CD34 (red)

Size profile of viral small RNAs obtained from control cells and RIG-I- and MDA5-deficient (KO) cells after infection for 24 h with SINV at an MOI of 0.1,

Candidates with a PVM localization.

Figure 4 Representative images of skin biopsy sample

SIRT1 DAPI SIRT1 DAPI DAPI

SEM images of S. aureus ATCC cells left untreated (A) or treated with polymyxin B (PMB; 99.5 mg/liter) (B), FADDI-019 (1× MIC) (C), FADDI-019 (4×

CRISPR/Cas9-mediated integration of HA-glmS/M9 at the PfHsp70x locus.

IVA can localize to and encase the forespore in the absence of VM

Appendix in prodromal and early measles.

Axonal swelling and impairment of dendritic development in Purkinje cells from Pex14ΔC/ΔC BL/ICR mouse upon treatment with BDNF. Axonal swelling and impairment.

FLC treatment results in an increase in ploidy in a significant fraction of cells. FLC treatment results in an increase in ploidy in a significant fraction.

Expression of EXP1-BirA

Cholera Toxin FhHDM-1 Merged

The distribution of Sias in tissues from 10-day postfertilization embryonated chicken eggs. The distribution of Sias in tissues from 10-day postfertilization.

Subcellular localization of UUKV, HRTV, and SFTSV NSs

Inhibition of VEGFA or macrophage-specific ablation of Vegfa from TIE2hi/VEGFAhi TMEM macrophages reduces vascular permeability and tumor cell intravasation.

Volume 2, Issue 4, Pages (October 2007)

RNA-FISH validation of male and female markers.

Fig. 3 CSF1 is expressed in human melanoma.

Morphology of cells used throughout the experiments.

Localization of PBANKA_ and PBANKA_ during blood and liver stage development. Localization of PBANKA_ and PBANKA_ during blood.

AS aggregates interact with SERCA in SH‐SY5Y cells

Inhibition of DDR1 prevents formation of polarized cysts in 3D.

CpG-A and CpG-B are distributed in different compartments in PDCs

Ectopic overexpression of WOR3 drives switching to the opaque cell type. Ectopic overexpression of WOR3 drives switching to the opaque cell type. (A) Visualization.

Dynamic ranges of anti-PnPS IgG Reference standard serum 007sp for each of 13 serotypes. Dynamic ranges of anti-PnPS IgG Reference standard serum 007sp.

Fig. 1. Representative images of the four cell lines using fluorescence microscopy. Representative images of the four cell lines using fluorescence microscopy.

The distribution of lamin C and emerin in lymphoblastoid cell lines.

The effects of a dominant negative mutant of lamin B1 on lamin distribution in HeLa cells. The effects of a dominant negative mutant of lamin B1 on lamin.

Fig. 1. Mitochondrial internalization in cardiomyocytes.

Indirect fluorescence assay of N. gruberi cells.

Fcp1 CTD phosphatase affects a broad range of transcripts in the +N and -N media. Fcp1 CTD phosphatase affects a broad range of transcripts in the +N and.

Presence of CGH-1 in the embryo.

Change in fluorescence of C. neoformans upon addition of DM262.

Two domains of KHC act to position the nucleus.

Exo70 is recruited to the plasma membrane at sites of mechanical wounding. Exo70 is recruited to the plasma membrane at sites of mechanical wounding. NRK.

hADAR1 and hADAR2 co-localize within the nucleolus.

The N-terminal α-helices of YopM mediate cellular uptake and are able to deliver proteins as cargo. The N-terminal α-helices of YopM mediate cellular uptake.

LC8 and its binding partners display broad cellular localization.

Depletion of EB1 with small interfering RNA reduces MT minus-end anchoring at the centrosome. Depletion of EB1 with small interfering RNA reduces MT minus-end.

Integrin β3 is dispensable for RhoA activity and contractility.

The absence of host Fbln5 results in increased apoptosis and decreased proliferation in Pan02 tumors. The absence of host Fbln5 results in increased apoptosis.

c-Fos in RFMes GABAergic neurons across groups.

Subnuclear localization of HA-tagged EBNA1 protein.

TbERP1, TbERP2, TbERP4, and TbERP8 localize to ERES in PCF cells.

(A) Correlation between the shear modulus (Fig

Morphologic changes induced in immortalized human podocytes after treatment with TGF-β1 (10 ng/mL, right) for 3 days when compared with control cells (left),

PTZ-induced c-Fos and Arc proteins in hippocampal dentate gyrus

Effective TcdB cell interactions correlate with endocytosis.

The absence of Krp1 does not alter capsule production nor chitooligomers and mannose distribution in cryptococcal cell surface. The absence of Krp1 does.

Septin ring formation and chitin-containing septum formation are aberrant in filaments formed in response to staurosporine. Septin ring formation and chitin-containing.

Construction and characterization of YF/NIEV chimera.

DNA damage-induced RPA foci in asynchronous cells labeled with BUdR.

Functional assessment of NF-κB activation in SKBR3 cells.

Expression of XCR1 in normal ovarian surface epithelium and the IOSE and borderline EOC cell lines. Expression of XCR1 in normal ovarian surface epithelium.

Targeting HR via CDK inhibition resensitizes recurrent cultures to temozolomide (TMZ). Targeting HR via CDK inhibition resensitizes recurrent cultures.

Binding and antiproliferative effects of ANG4043 and anti-HER2 mAbs on tumor cells. Binding and antiproliferative effects of ANG4043 and anti-HER2 mAbs.

Circulating leukocytes are undetectable in blood vessels of solid tumors in RIP1-Tag2 mice even after IL-15/IL-15Rα complex treatment. Circulating leukocytes.

Expression of HO-1 by the FAP+/F4/80+ tumoral macrophages.

GlcN-induced knockdown of PfHsp70x does not affect intraerythrocytic growth. GlcN-induced knockdown of PfHsp70x does not affect intraerythrocytic growth.

Analysis of dCas9 expression.

The isolated MAbs bind to cells infected with recombinant vaccinia viruses expressing various arenavirus GPCs as well as to cells infected with authentic.

Primary GBM cells are permissive to HCMV in vitro.

Presentation transcript:

PfHsp70x knockout does not inhibit export of PfEMP1 to the host cell. PfHsp70x knockout does not inhibit export of PfEMP1 to the host cell. Asynchronous 3D7 and PfHsp70x-KO parasites were fixed with acetone and stained with antibodies against the ATS domain of PfEMP1 and MAHRP1. DAPI was used to stain parasite cell nucleus. The images from left to right are phase, DAPI (blue), PfEMP1 (green), MAHRP1 (red), and fluorescence merge. Representative images are shown. David W. Cobb et al. mSphere 2017; doi:10.1128/mSphere.00363-17