Removing Reprogramming Roadblocks: Mbd3 Depletion Allows Deterministic iPSC Generation Justin Brumbaugh, Konrad Hochedlinger Cell Stem Cell Volume 13, Issue 4, Pages 379-381 (October 2013) DOI: 10.1016/j.stem.2013.09.012 Copyright © 2013 Elsevier Inc. Terms and Conditions
Figure 1 Reprogramming Dynamics for Mbd3 Knockout Cells Compared to Wild-Type Cells By day 7, nearly 100% of Mbd3 knockout cells have induced pluripotency following OKSM expression, fitting a deterministic model. The dynamics of reprogramming in wild-type cells differ, suggesting a stochastic model. Cell Stem Cell 2013 13, 379-381DOI: (10.1016/j.stem.2013.09.012) Copyright © 2013 Elsevier Inc. Terms and Conditions