Predictive Validity of a Medical-Related Cardiorespiratory Fitness Algorithm in Predicting Cardiovascular Disease– and All-Cause Mortality: Implications.

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Presentation transcript:

Predictive Validity of a Medical-Related Cardiorespiratory Fitness Algorithm in Predicting Cardiovascular Disease– and All-Cause Mortality: Implications for Integration Into Clinical Practice Ovuokerie Addoh, MBBS, Meghan K. Edwards, MS, Paul D. Loprinzi, PhD Mayo Clinic Proceedings Volume 91, Issue 9, Pages 1320-1321 (September 2016) DOI: 10.1016/j.mayocp.2016.06.008 Copyright © 2016 Mayo Foundation for Medical Education and Research Terms and Conditions

Figure Kaplan-Meier survival curve for all-cause mortality, comparing those above and below the median metabolic equivalent (MET) level (9.8) derived from cardiorespiratory fitness (CRF) equations2: EstimatedCRFwomen(METs)=14.7873+(Age∗0.1159)−(Age2∗0.0017)−(BMI∗0.1534)−(WC∗0.0085)−(RHR∗0.0364)+(Active∗0.5987)−(Smoker∗0.2994) EstimatedCRFmen(METs)=21.2870+(Age∗0.1654)−(Age2∗0.0023)−(BMI∗0.2318)−(WC∗0.0337)−(RHR∗0.0390)+(Active∗0.6351)−(Smoker∗0.4263) Age expressed in years. Body mass index (BMI) was determined from measured height and weight (kg/m2). Resting heart rate (RHR) (beats/min) was determined from radial palpation assessed over a 30-second period (multiplied by 2). Activity status was determined from self-report and defined as at least 2000 MVPA METs-min-month.7 Those above this threshold were coded as 1; otherwise, coded as 0. Smoking status was determined based on self-report. Current smoker was coded as 1; otherwise, coded as 0. Waist circumference (WC) expressed in centimeters. MVPA = moderate to vigorous physical activity. Mayo Clinic Proceedings 2016 91, 1320-1321DOI: (10.1016/j.mayocp.2016.06.008) Copyright © 2016 Mayo Foundation for Medical Education and Research Terms and Conditions