Percentage of pneumococcal isolates within each vaccine group for 2001 and 2004. Percentage of pneumococcal isolates within each vaccine group for 2001.

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Percentage of pneumococcal isolates within each vaccine group for 2001 and 2004. Percentage of pneumococcal isolates within each vaccine group for 2001 and 2004. Percentage of PCV7 among all isolates was 36% in 2001 and 14% in 2004 (P < .0001). Percentage of potentially PCV7–cross-reactive isolates was unchanged (30% vs 31%), and percentage of non-PCV7 isolates increased from 34% to 55% (P < .0001). Proportional penicillin nonsusceptibility is shown in hatched bars and was significantly higher among non-PCV7 isolates in 2004 (25%) versus 2001 (8%; P = .01). All P values reflect 2-tailed Fisher exact tests. Susan S. Huang et al. Pediatrics 2005;116:e408-e413 ©2005 by American Academy of Pediatrics