Effect of inhibition of phagocytosis on the production of reactive oxygen species (ROS) against Aspergillus fumigatus. Effect of inhibition of phagocytosis.

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Effect of inhibition of phagocytosis on the production of reactive oxygen species (ROS) against Aspergillus fumigatus. Effect of inhibition of phagocytosis on the production of reactive oxygen species (ROS) against Aspergillus fumigatus. ROS production by polymorphonuclear cells (PMN) (a) and peripheral blood mononuclear cells (PBMC) (b) (2.5×106 per mL) is shown after pre-incubation with cytochalasin-B (Cyto-B) (5 µg·mL–1) and stimulation with Aspergillus fumigatus conidia (5×107 per mL). Error bars indicate sem for four healthy and four CF donors. RLU: relative light unit. Shan F. Brunel et al. ERJ Open Res 2018;4:00068-2017 ©2018 by European Respiratory Society