Time Heals All Wounds … But Wounds Heal Faster with Lactobacillus

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Time Heals All Wounds … But Wounds Heal Faster with Lactobacillus Frank M. Davis, Katherine Gallagher Cell Host & Microbe Volume 23, Issue 4, Pages 432-434 (April 2018) DOI: 10.1016/j.chom.2018.03.018 Copyright © 2018 Elsevier Inc. Terms and Conditions

Figure 1 Modulation of Wound Microenvironment by CXCL12-Producing Lactobacillus Promotes Wound Healing On-site production and delivery of lactic acid by Lactobacillus within the wound produces a local pH reduction that inhibits action of CD26. In addition, increased release and bioavailability of CXCL12 results in macrophage accumulation and increased macrophage production of TGF-β, accelerating wound healing. Cell Host & Microbe 2018 23, 432-434DOI: (10.1016/j.chom.2018.03.018) Copyright © 2018 Elsevier Inc. Terms and Conditions