Atypical pemphigus involving the esophagus with IgG antibodies to desmoglein 3 and IgA antibodies to desmoglein 1 Shigeki Inui, MD, PhD, Masayuki Amagai,

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Presentation transcript:

Atypical pemphigus involving the esophagus with IgG antibodies to desmoglein 3 and IgA antibodies to desmoglein 1 Shigeki Inui, MD, PhD, Masayuki Amagai, MD, PhD, Shusaku Tsutsui, MD, PhD, Saho Fukuhara-Yoshida, MD, PhD, Satoshi Itami, MD, PhD, Ichiro Katayama, MD, PhD Journal of the American Academy of Dermatology Volume 55, Issue 2, Pages 354-355 (August 2006) DOI: 10.1016/j.jaad.2005.08.003 Copyright © 2006 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 A, Vesicles, pustules, and erosions were seen in periphery of erythema on trunk. Biopsy specimen showed neutrophilic spongiosis with eosinophil infiltration (B) and intraepidermal pustules throughout epidermis (C). (B and C, Hematoxylin-eosin stain, original magnifications: A, ×200; B, ×40.) Journal of the American Academy of Dermatology 2006 55, 354-355DOI: (10.1016/j.jaad.2005.08.003) Copyright © 2006 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 A, Multiple esophageal erosions (upper gastrointestinal fiberscope). B, Suprabasal desquamation of epithelia with lymphocyte and eosinophil infiltration. (Hematoxylin-eosin stain, original magnification: ×200.) Journal of the American Academy of Dermatology 2006 55, 354-355DOI: (10.1016/j.jaad.2005.08.003) Copyright © 2006 American Academy of Dermatology, Inc. Terms and Conditions