Diagram of the structures of several anchored surface proteins from various gram-positive bacteria. Diagram of the structures of several anchored surface proteins from various gram-positive bacteria. All surface proteins possess an N-terminal leader peptide (N) and a C-terminal cell wall sorting signal. Many surface proteins possess several repeating domains. Particularly striking are the Cα and Rib proteins ofS. agalactiae, which are composed of 9 or 12 nearly identical repeat domains, respectively (see the text). References for these proteins are given in Table 1. William Wiley Navarre, and Olaf Schneewind Microbiol. Mol. Biol. Rev. 1999; doi: