Cross-sectional and longitudinal associations between serum inflammatory cytokines and knee bone marrow lesions in patients with knee osteoarthritis 

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Cross-sectional and longitudinal associations between serum inflammatory cytokines and knee bone marrow lesions in patients with knee osteoarthritis  Z. Zhu, P. Otahal, B. Wang, X. Jin, L.L. Laslett, A.E. Wluka, B. Antony, W. Han, X. Wang, T. Winzenberg, F. Cicuttini, G. Jones, C. Ding  Osteoarthritis and Cartilage  Volume 25, Issue 4, Pages 499-505 (April 2017) DOI: 10.1016/j.joca.2016.10.024 Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Association between IL-6 and knee BMLs in total sample. (a) Baseline total knee BMLs (mean ± 95% CI), by quarters of baseline IL-6; (b) An increase in total knee BMLs over 2 years by quarters of baseline IL-6. Osteoarthritis and Cartilage 2017 25, 499-505DOI: (10.1016/j.joca.2016.10.024) Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Association between IL-17F, IL-23 and an increase in total knee BMLs over 2 years in females. Osteoarthritis and Cartilage 2017 25, 499-505DOI: (10.1016/j.joca.2016.10.024) Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions